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Effects of Whole Wrist Versus Specific Carpal Bone Mobilization in the Patients of Carpel Tunnel Syndrome

Effects of Whole Wrist Versus Specific Carpal Bone Mobilization in the Patients of Carpel Tunnel Syndrome

Status
Completed
Phases
Unknown
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT07724717
Enrollment
44
Registered
2026-07-24
Start date
2025-12-01
Completion date
2026-05-30
Last updated
2026-07-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Carpal Tunnel Syndrome

Keywords

Carpal Tunnel Syndrome, Manual Therapy, Range of Motion, Specific Carpal Bone Mobilization, Wrist Mobilization

Brief summary

The study was conducted to compare the effectiveness of Whole Wrist Mobilization versus Specific Carpal Bone Mobilization in reducing symptoms and improving function in patients with Carpal Tunnel Syndrome (CTS).

Interventions

OTHERSpecific Bone Mobilization

Scaphoid Mobilization: The therapist applied anterior-posterior mobilization on the scaphoid while the patient's wrist was in slight flexion. It was held for 5 seconds and repeated for 10 repetitions. Lunate Mobilization: The therapist performed lateral and medial mobilization of the lunate while stabilizing the forearm. It was held for 5 seconds and repeated for 10 repetitions. Triquetrum Mobilization: With the wrist in a neutral position, the therapist applied gentle mobilization to the triquetrum. It was held for 5 seconds and repeated for 10 repetitions.

OTHERWhole Wrist Mobilization

Distal Radioulnar Joint Mobilization: To perform mobilizations at the distal radioulnar joint, the therapist stabilized the patient's hand and radiocarpal region, then provided anteroposterior glide and medial and lateral rotary joint play movements of the distal ulna. Radiocarpal Joint - Dorsal Palmar Glide: The mobilization involved moving the row of carpal bones either dorsally to promote wrist extension or palmary to promote wrist flexion. Radiocarpal Joint - Ulnar and Radial Glide: Ulnar glide was performed to increase radial deviation, while radial glide was performed to increase ulnar deviation of the wrist joint. Mid-Carpal Joint Mobilization: The mobilization involved moving the row of carpal bones either dorsally to promote wrist extension or palmary to promote wrist flexion.

Hot Pack: A hot pack was applied to the wrist and forearm for 10 minutes to help relax the muscles and improve circulation around the carpal tunnel. Transcutaneous Electrical Nerve Stimulation: TENS was applied with a frequency of 2 Hz and a pulse duration of 200 µs for 10 minutes over the wrist area to reduce pain and discomfort. Wrist Flexion and Extension: With the arm supported, the patient actively flexed and extended the wrist through a full range of motion. This was repeated for 10 repetitions. Radial and Ulnar Deviation: With the arm supported, the patient actively moved the wrist side to side (radially and ulnarly). Wrist Circles: The patient performed circular motions with the wrist in both clockwise and counterclockwise directions. This was repeated for 10 repetitions. Wrist Flexor Stretch: The arm was extended in front with the palm facing up, and the fingers were gently pulled back to stretch the wrist flexors. The stretch was held for 30 seconds and repeated 3 times.

Sponsors

Riphah International University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)

Eligibility

Sex/Gender
ALL
Age
30 Years to 60 Years
Healthy volunteers
No

Inclusion criteria

* Participants aged 30 to 60 years old * Both male and female participants * CTS for at least 2 months * Pain levels on the Numeric Pain Rating Scale (NPRS) between 3 and 7 * Limited range of motion and wrist pain * Patient with positive PHALEN and TINEL test

Exclusion criteria

* Prior traumatic injury of wrist * History of wrist surgery * Diagnoses of polyneuropathy, cervical radiculopathy, myelopathy, inflammatory arthritis, diabetes, thyroid disease * Presence of abnormal sensation in the wrist region * Hemorrhagic tendency and/or current anticoagulation treatment * History of whiplash injury

Design outcomes

Primary

MeasureTime frameDescription
Numeric Pain Rating ScaleFrom enrollment to the end of treatment at 4 weeksThe Numeric Pain Rating Scale (NPRS) was used to assess pain intensity, with participants rating their pain from 0 (no pain) to 10 (worst possible pain). It provided a quantitative measure to track pain changes over time.
Boston Carpal Tunnel QuestionnaireFrom enrollment to the end of treatment at 4 weeksThe Boston Carpal Tunnel Questionnaire (BCTQ) is a recommended tool for assessing the functional status and severity of symptoms in CTS patients.
ROM Wrist FlexionFrom enrollment to the end of treatment at 4 weeksChanges in wrist flexion ROM at baseline and 4th week of intervention was measured using goniometer.
ROM Wrist ExtensionFrom enrollment to the end of treatment at 4 weeksChanges in wrist extension ROM at baseline and 4th week of intervention was measured using goniometer.
ROM Wrist Radial DeviationFrom enrollment to the end of treatment at 4 weeksChanges in wrist radial deviation ROM at baseline and 4th week of intervention was measured using goniometer.
ROM Wrist Ulnar DeviationFrom enrollment to the end of treatment at 4 weeksChanges in wrist ulnar deviation ROM at baseline and 4th week of intervention was measured using goniometer.

Countries

Pakistan

Contacts

PRINCIPAL_INVESTIGATORAli Raza, MS-OMPT

Riphah International University

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Jul 25, 2026