Tetanus
Conditions
Keywords
Healthy Adults, Vaccination, Protective Efficacy, Observational Study, TQS, tetanus
Brief summary
The goal of this observational study is to learn about antibody level of tetanus of adults in high-income city of china. The main question it aims to answer is: 1. Analysis of tetanus antibody distribution across different age groups 2. Evaluation of the TQS method for determining antibody status 3. Correlation between primary vaccination history and tetanus antibody concentrations Blood samples were voluntarily provided by adult healthy participants for tetanus antibody analysis over a continuous collection period of more than one year.
Interventions
None listed
Sponsors
Peking University First Hospital
Study design
Observational model
OTHER
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* Voluntarily sign the informed consent form； * Be aged 18 years or older； * Be willing to provide a blood sample for biochemical testing
Exclusion criteria
* Receipt of immunoglobulin, blood, or blood products within 6 months prior to enrollment； * Refusal to provide tetanus vaccination history (including vaccination records, CDC vaccine administration registry, or subject's recall)； * Individuals with recent tetanus vaccination (within 5 years), acute illness, pregnancy, or immunosuppressive conditions will be excluded
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Tetanus Antibody Level | Baseline (single blood draw at enrollment) | Single blood draw |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| tetanus antibody level by TQS/mTQS method | Baseline (single blood draw at enrollment) | at baseline |
Countries
China
Outcome results
None listed