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Effect of Implementing Cough Augmentation Techniques on Weaning Outcomes Among Critically Ill Patients

Effect of Implementing Cough Augmentation Techniques on Weaning Outcomes Among Critically Ill Patients

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT07722260
Enrollment
88
Registered
2026-07-23
Start date
2026-07-08
Completion date
2026-11-10
Last updated
2026-07-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Physiological Parameters

Keywords

cough augmentation, weaning outcomes

Brief summary

The study aims to determine the effect of implementing cough augmentation techniques on weaning outcomes among critically ill patients

Detailed description

Cough augmentation techniques are important interventions for critically ill patients who have impaired cough strength due to mechanical ventilation, neuromuscular weakness, sedation, or respiratory muscle dysfunction. These techniques, which include manual assisted cough, lung volume recruitment, and mechanical insufflation-exsufflation, enhance expiratory airflow and improve the clearance of airway secretions

Interventions

OTHERcough augmentation techniques

the lung volume recruitment maneuver via MV was applied with assistant of the attended physician as follows: Use pressure-controlled ventilation and increase end-inspiratory volume (30 or 40 cm H2O for 30 to 40 seconds unless contraindicated) or inspiratory hold for 30 to 40 seconds to promote cough effectiveness. The patient serially inhales a volume of gas without exhalation until maximum insufflation capacity via the ventilator to facilitate breath-holding (if not contraindicated).

Sponsors

Heba.Attia@nur.dmu.edu.eg
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE
Masking
SINGLE (Subject)

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* adult intubated patients * both sex

Exclusion criteria

* patient with facial trauma * patient with tracheostomy tube

Design outcomes

Primary

MeasureTime frameDescription
weaning successwithin 7 daysmeasured through successful extubating

Countries

Egypt

Contacts

CONTACTAlaa Mustafa, assistant professor
alaa.mustafa@nur.dmu.edu.eg0201097210526
CONTACTHeba Saad, lecturer
heba.attia@nur.dmu.edu.eg04501274855242
PRINCIPAL_INVESTIGATORsahar youness, professor

professor of critical care and emergency nursing

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Jul 24, 2026