Screening Questionnaires and Musculoskeletal Ultrasound for Early Detection of Spondyloarthritis in IBD Patients

Incremental Value of Musculoskeletal Ultrasound After DETAIL and IBIS-Q Screening for Early Detection of IBD-associated Spondyloarthritis.

Status

Not yet recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT07721844

Acronym

IBD-MSUS

Enrollment

200

Registered

2026-07-23

Start date

2026-09-01

Completion date

2027-12-01

Last updated

2026-07-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Inflamatory Bowel Disease, Spondylarthritis

Keywords

DETAIL questionnaire, IBIS-Q questionnaire, Musculoskeletal ultrasound, Screening, IBD

Brief summary

This study aims to evaluate the screening performance of the DETAIL and IBIS-Q questionnaires followed by musculoskeletal ultrasound (MSUS) for the early detection of spondyloarthritis in patients previously diagnosed with Inflammatory Bowel Disease (IBD).

Detailed description

Inflammatory bowel disease (IBD) is frequently associated with extraintestinal manifestations, with spondyloarthritis (SpA) being the most common. Early detection is crucial to prevent structural damage. This prospective study will screen consecutive adult patients with IBD using the DETAIL and IBIS-Q questionnaires. Patients will then undergo a comprehensive clinical and musculoskeletal ultrasound (MSUS) assessment to evaluate the incremental diagnostic value of ultrasound in detecting early and subclinical SpA.

Interventions

DIAGNOSTIC_TESTDETAIL .IBIS_Q . MSUS

All patients will be screened using the DETAIL and IBIS-Q questionnaires, followed by a comprehensive musculoskeletal ultrasound (MSUS) assessment.

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

Adult Aged 18 years old or more Confirmed diagnosis of IBD (by established clinical, endoscopic, and histopathological criteria). Patient provides informed written consent to participate

Exclusion criteria

Known, pre-existing diagnosis of Spondyloarthritis or any other concomitant systemic autoimmune rheumatic disease. Severe secondary osteoarthritis or major joint trauma/surgery mimicking SpA. Cognitive impairment or communication barriers preventing comprehension or completion of questionnaires

Design outcomes

Primary

Measure	Time frame	Description
Prevalence of undiagnosed spondyloarthritis	At the time of clinical evaluation (up to 12 months)	The percentage of patients with inflammatory bowel disease (IBD) who are newly diagnosed with spondyloarthritis based on DETAIL and IBIS-Q questionnaires followed by musculoskeletal ultrasound (MSUS).

Countries

Egypt

Contacts

CONTACTShaimaa Salah Abdelaziz, mbbch

shaima.17289546@med.aun.edu.eg01093098451

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Jul 24, 2026