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Diagnostic Accuracy of ONSD, ODE, and the Crescent Sign

Diagnostic Accuracy of ONSD, ODE, and the Crescent Sign on Ultrasound for Identifying Increased Intracranial Pressure: A Multicenter Study

Status
Not yet recruiting
Phases
Unknown
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT07719842
Enrollment
10
Registered
2026-07-22
Start date
2026-08-01
Completion date
2027-01-31
Last updated
2026-07-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Assessment of ONSD, ODE and the Crescent Sign Using POCUS

Keywords

POCUS, ONSD, ODE, crescent sign

Brief summary

Our aim was to determine the diagnostic accuracy of the ONSD, ODE, and crescent sign, as detected by POCUS, in identifying the clinical and radiological features of increased intracranial pressure.

Detailed description

All participants presenting to the ED with various symptoms and undergoing cranial CT or MRI for the diagnosis of cranial pathologies who do not meet the exclusion criteria will be included in the study. Informed consent will be obtained from all patients prior to the study. For participants included in the study, the presence of ONSD, ODE, and the crescent sign will be assessed using bedside ultrasound, and the diagnostic value of these findings will be evaluated. The bedside ultrasound will form part of the critical area examination in the emergency department; it will incur no cost to the institution and will be performed and assessed by an emergency medicine specialist and their assistant.

Interventions

DIAGNOSTIC_TESTUltrasound assessment

Determination of optic nerve sheath diameter (ONSD), optic disc elevation (ODE) and the presence of the crescent sign using bedside ultrasound

Sponsors

Recep Tayyip Erdogan University Training and Research Hospital
Lead SponsorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* All patients presenting at the ED with any symptoms, who have undergone a cranial CT or cranial MRI for the diagnosis of cranial pathologies, and who do not meet the

Design outcomes

Primary

MeasureTime frameDescription
Primary outcomeAn average of 8 monthsThe diagnostic value of ONSD, ODE and the crescent sign in increased intracranial pressure

Countries

Turkey (Türkiye)

Contacts

CONTACTMümin M Yazici, Specialist
mmuratyazici53@gmail.com+9005364971612

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Jul 23, 2026