Gingival Recession (Miller II)
Conditions
Brief summary
This study aims to evaluate the effect of injectable Platelet-Rich Fibrin (i-PRF) in combination with collagen membrane in the treatment of Miller Class II gingival recession. Gingival recession is a common periodontal condition characterized by apical displacement of the gingival margin, which may lead to aesthetic concerns, root hypersensitivity, and increased risk of root caries. The study will include patients diagnosed with Miller Class II gingival recession. Participants will be treated using a regenerative periodontal surgical approach involving coronally advanced flap combined with injectable platelet-rich fibrin and collagen membrane. Clinical parameters such as recession depth, clinical attachment level, and keratinized tissue width will be evaluated before and after treatment at specific follow-up intervals. The objective is to compare the effectiveness of this combined regenerative approach in improving root coverage and soft tissue healing, and to assess its potential benefits in periodontal regeneration and esthetic outcomes.
Interventions
PROCEDUREGroup (1)
Application of injectable platelet -rich fibrin (I-PRF) in combination with a collagen membrane during the surgical procedure to enhance soft and hard tissue healing
PROCEDUREGroup 2
coronally advanced flap surgery combined with a subepithelial connective tissue graft for the treatment of gingival recession defects
Sponsors
Tanta University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
Both males and females of age ≥ 18
Exclusion criteria
History of systemic diseases (i.e. diabetes, autoimmune dysfunction, prolonged cortisone therapy, or chemotherapy) that contraindicated periodontal surgical treatment.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Keratinized Tissue Thickness | Baseline, 1 month ,3 months and 6 months after surgery | measured in millimeters (mm) using a endodontic file |
Secondary
| Measure | Time frame |
|---|---|
| Recession Depth (RD) | baseline,1 month,3 months,6 months after surgery |
| Recession Width (RW) | Baseline,1 month,3 months ,and 6 months after surgery |
| keratinized Tissue Height (KTH) | Baseline, 1 month, 3 months, 6 months after surgery |
| Probing Pocket Depth (PPD) | Baseline and 6 months after surgery |
Countries
Egypt
Contacts
PRINCIPAL_INVESTIGATORShereen Abdelmoula Ali
Faculty of dentistry ,Tanta university .Tanta, Eygpt
Outcome results
None listed