Kidney Failure, Chronic, Renal Dialysis
Conditions
Keywords
Exercise, Hemodialysis, Quality of Life, Self-Esteem, Sexual Function
Brief summary
This randomized controlled trial compared intradialytic exercise with home-based exercise in married female patients receiving maintenance hemodialysis. Ninety participants were randomly assigned in equal numbers to an intradialytic exercise group, a home-based exercise group, or a control group. Both exercise programs continued for 12 weeks. The study evaluated whether exercise performed during dialysis or at home could improve quality of life, self-esteem, sexual function, and selected clinical and laboratory outcomes. Quality of life was assessed using the 36-Item Short Form Survey, self-esteem using the Rosenberg Self-Esteem Scale, and sexual function using the Female Sexual Function Index. Laboratory assessments included calcium, phosphorus, intact parathyroid hormone, albumin, C-reactive protein, hemoglobin, sodium, and potassium.
Interventions
BEHAVIORALIntradialytic Exercise
A supervised low- to moderate-intensity aerobic and resistance exercise program performed during the first two hours of hemodialysis, three times per week for 12 weeks.
BEHAVIORALHome-Based Exercise
A structured home-based exercise program consisting of walking, bodyweight resistance exercises, and flexibility routines for 30 minutes per day, at least three to five times per week for 12 weeks.
Sponsors
Tanta University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE
Masking
NONE
Intervention model description
Participants were randomly allocated in equal numbers to an intradialytic exercise group, a home-based exercise group, or a control group for 12 weeks.
Eligibility
Sex/Gender
FEMALE
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Female patients older than 18 years. * Clinically stable. * Receiving regular maintenance hemodialysis three times per week for at least three months. * Able to perform mild- to moderate-intensity exercise.
Exclusion criteria
* Physical limitations preventing exercise. * Acute illness. * Unstable cardiovascular disease. * Severe orthopedic or neurological disorders. * Cognitive impairment affecting cooperation. * Dialysis instability. * Severe chronic kidney disease-mineral and bone disorder. * Significant anemia. * Retinal hemorrhage. * History of hyperthyroidism.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Health-Related Quality of Life | Baseline and 12 weeks | Change in Health-Related Quality of Life was assessed by the 36-Item Short Form Survey. The 36-Item Short Form Survey consists of 36 items covering eight health domains: physical functioning, role limitations due to physical health, bodily pain, general health perceptions, energy/fatigue, social functioning, role limitations due to emotional problems, and emotional well-being. Each domain is scored from 0 to 100, with 0 representing the lowest possible health status and 100 representing the highest possible health status. Higher scores indicate better health-related quality of life. The validated Arabic version was used. |
| Self-Esteem | Baseline and 12 weeks | Change in Self-Esteem was assessed by the Rosenberg Self-Esteem Scale. The Rosenberg Self-Esteem Scale consists of 10 items assessing global self-esteem, including five positively worded and five negatively worded statements. Higher total scores indicate higher self-esteem. |
| Female sexual function | Baseline and 12 weeks | Change in Female Sexual Function was assessed by the Female Sexual Function Index. The Female Sexual Function Index consists of 19 items covering six domains of female sexual function: desire, arousal, lubrication, orgasm, satisfaction, and pain. The total score ranges from 2 to 36, with higher scores indicating better sexual function. The validated Arabic version was used. |
Countries
Egypt
Outcome results
None listed