Blood Cancer, Blood Cancers, Hematologic Cancer, Hematologic Malignancies, Hematologic Neoplasm, Hematologic Tumors, Leukemia, Lymphoma, Myeloma
Conditions
Keywords
genetics, blood cancer, blood cancers, leukemia, lymphoma, myeloma, hematologic cancer, hematologic malignancy, hematologic tumor, hematologic neoplasm
Brief summary
The goal of this study is to enroll at least 10,000 participants nationally including affecteds and unaffecteds via online study portal, collect surveys online and a saliva sample through the mail, sequence DNA, and conduct genetic analyses to identify novel variants and further study known variants associated with leukemia, lymphoma, myeloma and other blood cancers.
Detailed description
This is an online research study to learn more about how genes affect your risk of blood cancers. No office visit is required and in return, participants may receive information about their genetic ancestry for free. This study will increase our understanding of the genetic basis of blood cancers, which is a crucial step in drug development to improve current treatment options. We seek a diverse population because diversity among participants maximizes the usefulness of the data. Participants will use our online study portal to answer questions about their health and provide their DNA via a saliva sample using a pre-paid mailer. Participation takes approximately 20 minutes. Participants will be invited to share data from their electronic health records, but this is not required for study participation. We keep participants engaged with short monthly newsletters.
Interventions
None listed
Sponsors
Rutgers, The State University of New Jersey
Study design
Observational model
CASE_CONTROL
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
18 Years to 110 Years
Healthy volunteers
Yes
Inclusion criteria
* age 18 years or older * currently living in the United States * have access to the internet and a computer, laptop, tablet or smartphone * willing to provide written informed consent for participation * willing to provide DNA via a saliva sample using a collection kit mailed to your home * willing to complete a survey with questions about health related to the study of blood cancer.
Exclusion criteria
* Not able to meet or fulfill any of the inclusion criteria
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Genetic risk variants associated with blood cancer | 2 years | Genetic factors will be measured through whole exome sequencing and genome-wide genotyping array, and then correlated with blood cancer subtype. |
Countries
United States
Contacts
CONTACTTara Matise, PhD
PRINCIPAL_INVESTIGATORTara Matise, PhD
Rutgers University
Outcome results
None listed