Anxiety, Cancer, Chemotherapy
Conditions
Keywords
Artificial Intelligence, AI-Assisted Expressive Writing, Chemotherapy
Brief summary
This study aims to evaluate the effect of an AI-assisted expressive writing intervention on anxiety, emotional distress, and quality of life among patients receiving chemotherapy. A mixed-methods, interventional research design will be employed. Participants will be assigned to either a study group receiving the AI-assisted expressive writing program in addition to routine care or a control group receiving routine care only. Quantitative data will be collected using the Depression Anxiety Stress Scale-21 (DASS-21) and the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-Core 30 (EORTC QLQ-C30). Qualitative data will be obtained through semi-structured interviews to explore participants' experiences with the intervention. The findings are expected to provide evidence regarding the effectiveness of AI-assisted expressive writing as a supportive strategy for improving psychological well-being and quality of life among patients undergoing chemotherapy.
Interventions
BEHAVIORALAI-Assisted Expressive Writing
Participants will engage in an AI-assisted expressive writing program in addition to routine chemotherapy care. The intervention consists of guided writing sessions delivered through an artificial intelligence platform that provides structured prompts to facilitate emotional expression, self-reflection, and disclosure of thoughts and feelings related to cancer and chemotherapy experiences.
OTHERActive Comparator: Routine Care Group
Participants will receive routine chemotherapy care and standard nursing care provided by the oncology unit without participation in the AI-assisted expressive writing program.
Sponsors
Alexandria University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Adult patients aged 18 years and above. * Diagnosed with any type of cancer and currently receiving chemotherapy treatment. * Able to read and write Arabic. * Able to communicate and express thoughts and feelings. * Have access to a smartphone, tablet, or computer with internet connectivity. * Willing to participate in the study and provide informed consent.
Exclusion criteria
* Diagnosed with severe psychiatric disorders (e.g., psychosis or schizophrenia). * Having cognitive impairment that interferes with understanding or communication. * Currently receiving structured psychological therapy during the study period. * Unable to complete the study questionnaires or intervention sessions. * Refusal to participate or withdrawal from the study at any time.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change in Anxiety and Emotional Distress Scores | Baseline (Day 1) and Week 4 after intervention | Anxiety and emotional distress will be measured using the Depression Anxiety Stress Scale-21 (DASS-21). Changes in participants' scores will be assessed before and after the intervention. Higher scores indicate greater levels of psychological distress. |
| Change in Quality of Life Scores | Baseline (Day 1) and Week 4 after intervention | Quality of life will be assessed using the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-Core 30 (EORTC QLQ-C30). Changes in quality-of-life scores will be evaluated before and after the intervention. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Participants' Experiences with AI-Assisted Expressive Writing | Week 4 after intervention | Participants' perceptions and experiences regarding the AI-assisted expressive writing intervention will be explored through semi-structured interviews and analyzed using thematic analysis. |
Countries
Egypt
Contacts
CONTACTMohamed Fakhry Ahmed Salem, PhD
PRINCIPAL_INVESTIGATORMohamed Fakhry Ahmed Salem, PHD
Alexandria University
Outcome results
None listed