Comparison of Epidural and Intravenous Analgesia in Laparoscopic Sleeve Gastrectomy Patients

Comparison of the Effects of Epidural and Intravenous Analgesia on Postoperative Lung Functions in Patients Undergoing Laparoscopic Sleeve Gastrectomy Surgery

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT07712224

Acronym

EAvs IV in LSG

Enrollment

106

Registered

2026-07-17

Start date

2025-01-01

Completion date

2025-10-15

Last updated

2026-07-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bariatric Surgery, Laparoscopic Sleeve Gastrectomy, Obesity

Keywords

Epidural Analgesia, Intravenous Analgesia, Pulmonary Function, FEV1, Postoperative Analgesia, Obesity, Bariatric Surgery

Brief summary

This retrospective observational study aimed to compare the effects of epidural analgesia and intravenous analgesia on early postoperative pulmonary function in patients undergoing laparoscopic sleeve gastrectomy. Preoperative and postoperative pulmonary function tests, pain scores, opioid consumption, and intraoperative respiratory parameters were evaluated.

Detailed description

This retrospective observational study was conducted at Trabzon Kanuni Training and Research Hospital. Adult patients who underwent laparoscopic sleeve gastrectomy between January 2025 and October 2025 were included. Patients were divided into two groups according to postoperative analgesia technique: epidural analgesia and intravenous analgesia. The primary outcome was postoperative change in FEV1 at 24 hours after surgery. Secondary outcomes included changes in FVC and FEV1/FVC ratio, postoperative pain scores, additional opioid consumption, and intraoperative ventilatory parameters including peak airway pressure and plateau pressure. Demographic data, perioperative variables, pulmonary function test results, arterial blood gas analyses, and analgesia-related data were retrospectively collected from hospital records. The study was approved by the Non-Interventional Scientific Research Ethics Committee of Trabzon University Faculty of Medicine.

Interventions

PROCEDUREEpidural analgesia (0.125% bupivacaine/2mcg fentanyl solution)

Thoracic epidural catheter-based analgesia using bupivacaine and fentanyl for postoperative pain management.

DRUGIntravenous analgesia

Intravenous tramadol-based patient-controlled analgesia for postoperative pain management.

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 65 Years

Healthy volunteers

Inclusion criteria

* Adult patients aged 18-65 years * ASA physical status III * Undergoing laparoscopic sleeve gastrectomy * Availability of preoperative and postoperative pulmonary function tests * Availability of arterial blood gas analysis data * Receipt of epidural or intravenous postoperative analgesia

Exclusion criteria

* Missing pulmonary function test data * Incomplete medical records * Conversion to open surgery * Severe respiratory disease affecting pulmonary function assessment

Design outcomes

Primary

Measure	Time frame	Description
Change in FEV1 at 24 Hours After Surgery	Preoperative period and postoperative 24 hours	Assessment of postoperative change in forced expiratory volume in 1 second (FEV1) measured before surgery and at postoperative 24 hours.

Countries

Turkey (Türkiye)

Contacts

PRINCIPAL_INVESTIGATOResra kongur, M.D

Trabzon Kanuni Training and Research Hospital

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Jul 18, 2026