Nausea and Vomiting, Postoperative, Pain, Pain Catastrophizing, Vomiting, Postoperative
Conditions
Keywords
The Pain Catastrophizing Scale, Postoperative Nausea and Vomiting, Laparoscopic Cholecystectomy
Brief summary
This study aims to explore whether patients' tendency to exaggerate or focus on pain (pain catastrophizing) is related to experiencing nausea and vomiting after surgery. The study will include patients undergoing laparoscopic cholecystectomy. Before surgery, patients will answer questions measuring pain catastrophizing and rate their pain during intravenous cannulation. Nausea and vomiting will be assessed at various times during the first 24 hours after surgery. The results may help better understand how psychological factors affect postoperative symptoms.
Detailed description
This study is designed as a prospective, cross-sectional, and observational study. The Pain Catastrophizing Scale (PCS) is a well-established self-report instrument developed to assess catastrophic thinking related to pain. It evaluates how individuals perceive and respond to pain, focusing on tendencies such as rumination, magnification, and feelings of helplessness. Evidence suggests that PCS is a strong predictor of pain intensity, independent of anxiety levels. In this study, the validated Turkish version of the Pain Catastrophizing Scale will be used. Postoperative nausea, vomiting, and retching are common adverse events that can complicate recovery from anesthesia. Patients often perceive these symptoms as more distressing than postoperative pain, and they represent important outcomes affecting patient satisfaction and recovery. The present study aims to investigate the relationship between pain perception during intravenous (IV) cannulation, pain catastrophizing levels, and postoperative nausea and vomiting. By evaluating numeric pain scores during IV access alongside PCS scores, this study seeks to explore whether preoperative pain perception and psychological factors are associated with the frequency of postoperative nausea and vomiting. The findings of this study are expected to contribute to a better understanding of the role of psychological factors in postoperative symptoms and may help improve anesthesia practices by supporting more individualized, patient-centered perioperative care.
Interventions
None listed
Sponsors
Trabzon Kanuni Education and Research Hospital
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
Yes
Inclusion criteria
* Adult patients aged 18-65 years * American Society of Anesthesiologists (ASA) physical status I-II-III * Scheduled for elective laparoscopic cholecystectomy * Able to provide informed consent
Exclusion criteria
* Age \<18 or \>65 years * Emergency surgery * ASA physical status \> III * Pregnancy * Chronic opioid use * Known drug allergy * Psychiatric disorders * Neurological diseases (central or peripheral neuropathy) * History of cerebrovascular disease (stroke) * Chronic renal disease * Chronic pulmonary disease * Patients who refuse to participate
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Incidence of postoperative nausea and vomiting (PONV) | Within 24 hours postoperatively | The primary outcome is the incidence of postoperative nausea and vomiting (PONV) according to preoperative Pain Catastrophizing Scale (PCS) scores. Patients will be evaluated for PONV at 0, 3, 6, 12, and 24 hours postoperatively. The relationship between PCS scores and the frequency of PONV will be analyzed. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Association between IV cannulation pain and pain catastrophizing | Preoperative period | The secondary outcome is the relationship between pain experienced during intravenous (IV) cannulation and preoperative Pain Catastrophizing Scale (PCS) scores. Pain during IV access will be measured using a numeric rating scale (0-10). The association between IV pain scores and PCS scores will be analyzed |
Countries
Turkey (Türkiye)
Contacts
CONTACTsedanur sula
Outcome results
None listed