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Efficacy of Ivermectin in the Treatment of Plane Warts

A Prospective Randomized Controlled Clinical Trial to Evaluate the Efficacy of Oral and Topical Ivermectin in the Treatment of Plane Warts

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT07710638
Enrollment
80
Registered
2026-07-17
Start date
2026-06-01
Completion date
2027-06-01
Last updated
2026-07-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Plane Warts

Keywords

ivermectin

Brief summary

This study aims to evaluate the efficacy of ivermectin in the treatment of plane warts( flat warts). patients diagnosed with plane warts will be included to assess the clearance ratre of the lesions.

Interventions

DRUGIvermectin

An antiparasitic medication evaluated for its immunomodulatory and antiviral efficacy in clearing plane warts. it will be administered to patients according to their assigned group protocol.

OTHERPlacebo

Patients in the control group will receive placebo,they will undergo standard clinical observation and follow up to monitor the natural course of the plane warts.

Sponsors

Al-Azhar University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
5 Years to No maximum
Healthy volunteers
No

Inclusion criteria

• Clinical and dermoscopic diagnosis of the plane warts. * No prior treatment for warts in the last 4 weeks. * Patients of both sex (male - female) * Age more than 5 years or weight more than 15 kg.

Exclusion criteria

* • Patients with other types of warts (e.g., common, plantar, genital). * History of hypersensitivity or allergy to ivermectin or its components. * Patients who have received systemic immunosuppressive therapy within the last 3 months. * Presence of chronic skin conditions that may interfere with evaluation (e.g., eczema, psoriasis). * Patients with immunodeficiency disorders (e.g., HIV, organ transplant recipients). * Pregnant or lactating females. * Patients currently on systemic antiviral or immunomodulatory treatment.

Design outcomes

Primary

MeasureTime frame
percentage of patients achieving complete clearance of plane warts3 months

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Jul 18, 2026