Biomarkers, Dental Caries, Matrix Metalloproteinase 8, Osteoporosis
Conditions
Brief summary
This study examines saliva samples from patients with osteoporosis. The levels of cytokines and Matrix Metalloproteinase-8 (MMP-8) enzyme in saliva will be measured. Additionally, the dental caries status of participants will be evaluated. The aim of this study is to understand the relationship between osteoporosis and oral health. Only saliva samples will be collected from participants; no treatment or medication will be administered.
Interventions
None listed
Sponsors
Afyonkarahisar Health Sciences University
Study design
Observational model
CASE_CONTROL
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
45 Years to 75 Years
Healthy volunteers
Yes
Inclusion criteria
* Willing to give voluntary consent For Group 1, having been diagnosed with osteoporosis For Group 2, being systemically healthy and not having a diagnosis of osteoporosis/osteopenia
Exclusion criteria
* Having a chronic inflammatory or autoimmune disease Using glucocorticoids, anti-anxiety medications, antidepressants, or antiepileptic drugs Having been diagnosed with any malignancy Having any endocrine disease Having undergone periodontal treatment within the last 6 months
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Salivary Cytokine Levels | day 1 | Measurement of cytokine levels in saliva samples collected from osteoporosis patients |
Contacts
CONTACTKübra Karaçam, Asist.Prof.
Outcome results
None listed