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Total Lower Uterine Segmentectomy With Adjunctive Mechanical Towel Compression for the Surgical Management of Placenta Accreta Spectrum Disorders

Total Lower Uterine Segmentectomy With Adjunctive Mechanical Towel Compression for the Surgical Management of Placenta Accreta Spectrum Disorders: A Case Series

Status
Not yet recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT07706062
Enrollment
30
Registered
2026-07-15
Start date
2026-09-01
Completion date
2027-12-01
Last updated
2026-07-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Placenta Accreta Management

Keywords

placenta accreta

Brief summary

The goal of this observational study is to evaluate the feasibility and safety of utilizing adjunctive mechanical towel compression during TLS-CCA, measured primarily by estimated intraoperative blood loss in patient with Maternal age 18-45 years - Singleton pregnancy - Antenatal diagnosis of PAS (ultrasound ± MRI) - Planned elective cesarean delivery - Candidate for uterine preservation via TLS-CCA - Provided written informed consent

Detailed description

Placenta accreta spectrum (PAS) disorders, characterized by abnormal trophoblastic invasion into the myometrium, have seen a global rise in incidence primarily driven by increasing cesarean delivery rates. Massive obstetric hemorrhage remains the leading cause of maternal morbidity and mortality in these cases. While cesarean hysterectomy is the traditional gold standard for severe PAS, uteruspreserving procedures are increasingly preferred by patients desiring future fertility. Total lower uterine segmentectomy with cervico-corporeal anastomosis (TLS-CCA) is a recognized conservative technique that involves excising the invaded lower segment and reconstructing the uterus. Despite removing the primary placental implantation site, diffuse bleeding from the highly vascularized remaining myometrial bed, dissected bladder flap, and pelvic collateral vessels often persists. While traditional compression sutures or specialized devices are utilized for hemostasis, they can be costly or technically challenging in distorted anatomies. This study introduces a novel, simple, and cost-effective approach: the use of tightly rolled sterile surgical towelsapplied as direct mechanical compression against the lower uterine segment and bladder bed during dissection and reconstruction.

Interventions

None listed

Sponsors

Assiut University
Lead SponsorOTHER

Study design

Observational model
OTHER
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
FEMALE
Age
18 Years to 45 Years

Inclusion criteria

* Maternal age 18-45 years * Singleton pregnancy * Antenatal diagnosis of PAS (ultrasound ± MRI) * Planned elective cesarean delivery * Candidate for uterine preservation via TLS-CCA * Provided written informed consent

Exclusion criteria

* Hemodynamic instability necessitating emergency hysterectomy * Placental invasion into adjacent pelvic organs requiring exenteration * Pre-existing severe coagulation disorders * Multiple gestation or major fetal anomalies * Patient refusal to participate

Design outcomes

Primary

MeasureTime frameDescription
Estimated intraoperative blood lossat operationEstimated intraoperative blood loss by (mL)

Secondary

MeasureTime frameDescription
Blood transfusion requirementsintraoperativeBlood transfusion requirements (units of packed RBCs and FFP)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Jul 28, 2026