Role Of Fixed Prosthodontic Restorations on Metabolic Control of Ischemic Heart Disease Patients

Effect of Fixed Prosthodontic Rehabilitation on Nutritional and Metabolic Parameters in Patients With Ischemic Heart Disease

Status

Completed

Phases

Unknown

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT07705672

Enrollment

Registered

2026-07-15

Start date

2024-01-01

Completion date

2025-11-30

Last updated

2026-07-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ischemic Heart Disease

Brief summary

This study evaluated the effect of fixed prosthodontic rehabilitation on metabolic parameters and masticatory efficiency in patients with ischemic heart disease. Clinical and laboratory outcomes was assessed before and after treatment.

Interventions

PROCEDUREFixed Prosthodontic Rehabilitation

Placement of fixed prosthodontic restorations to replace missing teeth and improve masticatory function.

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

45 Years to 70 Years

Healthy volunteers

Inclusion criteria

* Patients aged 45 to 70 years with diagnosed stable ischemic heart disease. * Patients presenting with partial edentulism and compromised masticatory function due to missing teeth. * Patients indicated for fixed prosthodontic rehabilitation. * Patients with complete clinical records and laboratory data available at baseline and 6 months after treatment. * Patients who provided informed consent for treatment and use of their clinical data.

Exclusion criteria

* uncontrolled systemic diseases affecting metabolic status (e.g., uncontrolled diabetes mellitus). * acute cardiovascular events or unstable ischemic heart disease. * Patients with conditions affecting oral function other than tooth loss (e.g., neuromuscular disorders). * Patients who received removable prostheses instead of fixed prosthodontic rehabilitation. * Patients with incomplete clinical records or missing baseline or 6-month laboratory data.

Design outcomes

Primary

Measure	Time frame	Description
Change in Hemoglobin A1c (HbA1c)	Baseline and 6 months after fixed prosthodontic rehabilitation	Hemoglobin A1c (HbA1c) (%) measured using standard laboratory methods. The mean change in HbA1c from baseline to 6 months after fixed prosthodontic rehabilitation will be assessed.
Change in High-Density Lipoprotein Cholesterol (HDL-C)	Baseline and 6 months after fixed prosthodontic rehabilitation	High-density lipoprotein cholesterol (HDL-C) concentration (mg/dL) measured using standard laboratory blood analysis. The mean change in HDL-C from baseline to 6 months after fixed prosthodontic rehabilitation will be assessed.
Change in Low-Density Lipoprotein Cholesterol (LDL-C)	Baseline and 6 months after fixed prosthodontic rehabilitation	Low-density lipoprotein cholesterol (LDL-C) concentration (mg/dL) measured using standard laboratory blood analysis. The mean change in LDL-C from baseline to 6 months after fixed prosthodontic rehabilitation will be assessed.

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Jul 16, 2026