Interfascial Abdominal Wall Block for Gynecological Laparoskopy: A Randomized Clinical Trial

Combined Rectus Sheath and Quadratus Lumborum Blocks Versus Quadratus Lumborum Block Alone for Movement-evoked Pain After Laparoscopic Gynecologic Surgery: a Prospective Randomized Open-label Trial

Status

Completed

Phases

Unknown

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT07705516

Enrollment

Registered

2026-07-15

Start date

2025-01-07

Completion date

2025-12-28

Last updated

2026-07-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pelvic Pain, Postoperative Pain

Keywords

Quadratus Lumborum Block, Rectus Sheath Block, Laparoscopy, Gynecologic Surgical Procedures

Brief summary

The purpose of this study is to evaluate the clinical efficacy of combining ultrasound-guided bilateral rectus sheath blocks (RSB) and quadratus lumborum blocks (QLB) compared to using a quadratus lumborum block alone for postoperative analgesia in patients undergoing laparoscopic gynecological surgeries. The primary objective is to assess movement-evoked pain scores in the early postoperative period. Secondary objectives include the evaluation of postoperative opioid consumption, intraoperative hemodynamic stability, and the overall incidence of side effects. Investigators hypothesize that the combined interfacial abdominal wall block technique will provide superior pain relief and reduce opioid requirements during recovery.

Interventions

PROCEDUREBilateral QLB and RSB

Preoperative regional anesthesia. Bilateral QL block combined with bilateral RS block. Ultrasound-guided technique. Using local anesthetics.

PROCEDUREBilateral QLB alone

Preoperative regional anesthesia. Isolated bilateral QL block. No rectus sheath block. Ultrasound-guided technique. Using local anesthetics.

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

FEMALE

Age

25 Years to 65 Years

Healthy volunteers

Inclusion criteria

* Scheduled for elective gynecological video-laparoscopic surgery. * ASA physical status І-ІІ. * Age between 18 and 65 years. * Patient's informed consent to participate in the study

Exclusion criteria

* Known allergy or contraindications to local anesthetics. * Infection at the potential needle insertion sites. * Coagulopathy or ongoing anticoagulant therapy. * Conversion to open laparotomy during surgery. * Severe cognitive impairment or psychiatric disorders.

Design outcomes

Primary

Measure	Time frame	Description
Postoperative pain intensity	At 2, 4, 6, 12, and 24 hours postoperative assessment	Visual Analog Scale (VAS) score. Scale from 0 to 10. 0 means no pain. 10 means worst pain. Lower scores sindicate less pain.

Secondary

Measure	Time frame	Description
Total opioid consumption. Postoperative period. Measured in milligrams.	Within 24 hours after surgery.	Total dose of opioid analgesics. Administered within 24 hours. Measured in milligrams (mg). Lower doses indicate better opioid-sparing effect.

Countries

Ukraine

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Jul 16, 2026