Optimising the Cancer Management of Older Patients by Early and Specific Geriatric Interventions.

Optimization of Care in Older Patients With Cancer Undergoing Treatment in Day Care Unit, Through a Specific Management Based on Early Geriatric Warning Signs: a Multicenter Randomized Trial.

Status

Not yet recruiting

Phases

Unknown

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT07704307

Acronym

WARNING

Enrollment

1010

Registered

2026-07-15

Start date

2026-09-01

Completion date

2031-01-01

Last updated

2026-07-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Geriatric Oncology, Neoplasms (Cancer / Tumors)

Brief summary

The WARNING project proposes a new care organisation for older patients with cancer. The aim is to optimise management in daycare with early detection signs of geriatric syndromes and specific interventions. This prevention package, called the 'WARNING Pack', includes a specific multimodal geriatric management guide for the oncologist (physician form), based on patient-reported early geriatric warning signs (patient form). Primary outcome is to reduce the risk of deterioration in global quality of life at 6 months during treatment and to prevent the onset of geriatric syndromes.

Interventions

OTHERWARNING Pack

This prevention package, called the 'WARNING Pack', includes a specific multimodal geriatric management guide for the oncologist (physician form), based on patient-reported early geriatric warning signs (patient form).

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

SUPPORTIVE_CARE

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

75 Years to No maximum

Healthy volunteers

Inclusion criteria

* Patients aged ≥75 years. * Patients with confirmed solid cancer or haematological malignancy, regardless of * the site of the tumour (single or multiple), - the duration of the disease, or - the treatment modality (adjuvant, neoadjuvant, locally advanced, palliative metastatic). * Patients starting a first line of systemic treatment or a new line of treatment after a break of at least six months. * Patients treated in a daycare hospital. * Persons belonging to or benefiting from a social security scheme. * Free and informed consent after receiving appropriate information.

Exclusion criteria

* Patients under legal protection (guardianship, curatorship). * Persons with enhanced protection, i.e. persons deprived of their liberty by a judicial or administrative decision, persons in a health or social care institution, persons under legal protection and patients in emergency situations.

Design outcomes

Primary

Measure	Time frame
Proportion of patients with unchanged or improved global quality of life between M0 and M6.	6 month

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Jul 23, 2026