Study on the Effect of Fecal Microbiota Transplantation on Eradication of Refractory Helicobacter Pylori Infection

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT07704255

Enrollment

Registered

2026-07-15

Start date

2026-07-20

Completion date

2026-12-31

Last updated

2026-07-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Helicobacter Pylori Infection

Keywords

washed microbiota

Brief summary

To determine whether regulating the gut microbiota can contribute to the eradication of refractory H. pylori infection.

Interventions

BIOLOGICALtransanal fecal bacteria transplant

Received transanal fecal bacteria transplant

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to 80 Years

Healthy volunteers

Inclusion criteria

* 1\. Ages 18-70 * 2\. Hp infection treatment failed ≥4 times with guidelines-recommended therapies * 3\. Patients with early gastric cancer, peptic ulcer, gastric MALT lymphoma, atrophic gastritis and other diseases requiring the eradication of Hp.

Exclusion criteria

* 1\. Antibiotics and bismuth were taken within 4 weeks before this treatment; Or had taken PPI, H2 receptor antagonist, P-CAB within 2 weeks prior to treatment; * 2\. Pregnant or lactating women; * 3\. Those who are allergic to the investigational drugs used in this test or have contraindications; * 4\. Participated in other drug trials within 3 months before the treatment of this trial; * 5\. There are other serious diseases that affect the evaluation of this study at the same time, or they cannot correctly express their own complaints and cannot cooperate; * 6\. Subjects with dysphagia; * 7\. Patients with malignant tumors, serious concomitant diseases, severe ulcer bleeding or perforation; * 8\. Patients judged by the investigator to be unsuitable for clinical trials. * 9\. Those who do not want to sign the informed consent for the study.

Design outcomes

Primary

Measure	Time frame	Description
Whether Hp is successfully eradicated	2years	The successful eradication of Hp was determined by 13C urea breath test, immunohistochemical staining of Hp and Hp culture.test, immunohistochemical staining of gastric mucosa and Hp culture

Countries

China

Contacts

CONTACTGao Caiping, Doctor

gaocaip@126.com17708130286

CONTACTXia Yuehan, Master

694159760@qq.com13438917607

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Jul 16, 2026