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Pilot Study to Study the Time Between Pleuropulmonary Ultrasound and Antibiotic Therapy Prescription in Patients Admitted to the Emergency Department for Suspected Pneumonia

Pilot Study to Study the Time Between Pleuropulmonary Ultrasound and Antibiotic Therapy Prescription in Patients Admitted to the Emergency Department for Suspected Pneumonia

Status
Not yet recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT07703852
Acronym
PRE-EPPA
Enrollment
15
Registered
2026-07-14
Start date
2026-07-13
Completion date
2026-09-30
Last updated
2026-07-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pneumonia

Keywords

Pneumonia, Pleuropulmonary ultrasound, Antibiotic

Brief summary

Pneumonia is a common pathology with significant morbidity and mortality. It is recommended in his diagnostic approach to perform either a chest X-ray or a pleuropulmonary ultrasound. Previous studies have shown the advantages of ultrasound in terms of diagnostic performance cost and patient irradiation. However, it remains little used in clinical practice.

Detailed description

The study will be conducted in the Emergency Department of grenoble University Hospital. Patient admitted to the emergency department for respiratory symptoms (cough, fever, and/or dyspnea) will be enrolled in the study according to the inclusion and non-inclusion criteria and after obtaining his consent. The investigator will perform the pleuropulmonary ultrasound following the clinical examination carried out by the physician in charge of the patient. The patient's care is unaffected by the pleuropulmonary ultrasound's outcome, which is unknown to the physician in charge of the patient. Data collection after the patient's discharge from the emergency department.

Interventions

PROCEDUREPleuropulmonary ultrasound performed by the investigator for patient with suspicion od Pneumonia

In addition to the traditional management done by the physician at the patient's expense (such as clinical examination and paraclinical examinations like biology, chest X-ray, etc.), the investigator will perform pleuropulmonary ultrasound.

Sponsors

University Hospital, Grenoble
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Patient over 18 years admitted the the emergency department of Grenoble Alpes University Hospital with respiratory symptoms (cough and/or dyspnea, fever). * No objection by the subject to the study * Affiliated to the french social security system (or equivalent)

Exclusion criteria

* Patient admitted to a life-threatening emergency * Patient already on antibiotic therapy on admission * Patient excluded from another study * Patient with respiratory signs following chest trauma * Unable to communicate or non-french speaking patients or those with impaired comprehension or consciousness * Protected persons referred to in articles L1121-6 and L1121-8 of French public health code (deprived of liberty, tutorship or curatorship) * The patient already enrolled in the study

Design outcomes

Primary

MeasureTime frameDescription
Time between the antibiotic prescription and the pleuropulmonary ultrasonography used to detect pneumonia1 hourTime between the antibiotic prescription and the pleuropulmonary ultrasonography used to detect pneumonia

Secondary

MeasureTime frameDescription
Calculation of the predictive values of the pleuropulmonary ultrasound for pneumonia diagnosis1 dayCalculation of the predictive values of the pleuropulmonary ultrasound for pneumonia diagnosis: area under the curve, sensitivity, specificity, positive predictive value, negative predictive value.
duration of performing the pleuropulmonary ultrasound5 minutesduration of performing the pleuropulmonary ultrasound
Time between the patient's admission to the emergency department and the completion of the pleuropulmonary ultrasound1 hourTime between the patient's admission to the emergency department and the completion of the pleuropulmonary ultrasound
4. Time between the performance of the pleuropulmonary ultrasound and the performance of the chest X-ray2 hours4\. Time between the performance of the pleuropulmonary ultrasound and the performance of the chest X-ray

Contacts

CONTACTAlice GREMBER, MD
AGrember@chu-grenoble.fr0033476766784
CONTACTMarcelline BUFFIN
Mbuffin@chu-grenoble.fr0033476766784
PRINCIPAL_INVESTIGATORAlice GREMBER, MD

University Hospital, Grenoble

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Jul 15, 2026