Delayed Implant, Hyaluronic Acid (HA), Implant Placement, Surface Treatment, Tooth Loss, UV Dental Implant
Conditions
Keywords
Photofunctionalization, Ultraviolet (UV) treatment, Hyaluronic acid, Dental implants, Posterior maxilla, Osseointegration, Implant stability
Brief summary
This randomized clinical trial evaluates the effect of UV photofunctionalization and hyaluronic acid on dental implants placed in the posterior maxilla. Clinical and radiographic outcomes will be assessed during follow-up
Detailed description
The study compares conventional implants, UV-photofunctionalized implants, and UV-photofunctionalized implants with hyaluronic acid application in the posterior maxilla. Implant stability and peri-implant tissue changes will be evaluated clinically and radiographically during follow-up.
Interventions
PROCEDUREDelayed dental implant placement without photofunctionalization.
Delayed dental implants placed without photofunctionalization or hyaluronic acid in the posterior maxilla.
PROCEDUREDelayed dental Implant photofunctionalization before placement
Delayed dental implants photofunctionalized with UV light before placement in the posterior maxilla.
PROCEDUREDelayed dental Implant photofunctionalization and hyaluronic acid application before placement.
Delayed dental implants photofunctionalized with UV light and treated with hyaluronic acid before placement in the posterior maxilla.
Sponsors
Mansoura University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to 60 Years
Healthy volunteers
No
Inclusion criteria
* Patients with missed single tooth or multiple teeth in posterior maxilla. * Patients Free from any para-functional habits. * Patient with Adequate inter-arch relation and inter-occlusal space to accommodate the prosthetic restoration. * Patient with good oral hygiene. * Patients Willing to participate in the study's follow-up intervals.
Exclusion criteria
* Patients with any local or systemic disease that absolute contraindicate implant placement or surgery. * Pregnancy. * Patients with any pathological lesion or aggressive periodontal disease at the planned surgical site. * Patients on drugs that could affect bone healing process such as bisphosphonate. * Heavy Smokers for more than 10 cigarettes a day. * Uncooperative patients.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Hard Tissue (peri-implant bone) | - Immediately postoperative - 3 months after implant placement - 9 months after implant placement. | Marginal bone loss will be assessed using CBCT measured in mm. |
| Implant Stability | -immediately after implant placement -2 weeks postoperatively -4 weeks postoperatively - 3 months postoperatively - 9 months postoperatively | Implant stability will be evaluated using Osstell device based on resonance frequency analysis (ISQ values). |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Soft Tissue | -After 3 months postoperatively. -After 9 months postoperatively. | The peri-implant mucosa will be evaluated for signs of inflammation using the Modified Sulcus Bleeding Index (mSBI). |
| Peri-implant probing depth | After 3 months postoperatively. -After 9 months postoperatively. | Probing depth will be assessed using a calibrated periodontal probe and measured in mm. |
Countries
Egypt
Outcome results
None listed