Skip to content

Effects of Squat Variations on Quadriceps Muscle Thickness and Strength

Effects of Squat Variations on Quadriceps Muscle Thickness and Strength

Status
Completed
Phases
Unknown
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT07700641
Enrollment
42
Registered
2026-07-14
Start date
2026-04-27
Completion date
2026-07-20
Last updated
2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Exercise Physiology, Muscle Strength and Oxygenation

Keywords

Squat exercise, Resistance training, Muscle strength, Muscle oxygenation, Exercise physiology

Brief summary

The study was conducted using a randomized controlled trial design. Participants who met the inclusion criteria were randomly assigned to either the "Classic Squat Group" or the "Heel-Elevated Squat Group." Both groups completed an 8-week strength training program consisting of three sessions per week, following the resistance exercise principles recommended by the American College of Sports Medicine. The main component of the program was the assigned squat variation. Baseline and post-intervention assessments at 8 weeks were performed according to standardized protocols. Exercise sessions were supervised by an experienced physiotherapist to ensure proper technique and minimize injury risk. Training intensity was progressively increased based on participants' adaptation and one-repetition maximum (1-RM) strength levels.

Interventions

OTHERTradional Squat Group

Participants completed an 8-week supervised bodyweight squat program performed twice weekly, with progressive increases in training volume and intensity. Squats were performed to approximately parallel depth, using a controlled \~2-s eccentric phase followed by maximal intended concentric velocity, with 2-min rest intervals between sets.

OTHERHeel-Elevated Squat Group

Participants in the Heel-Elevated Squat Group performed all repetitions with both heels supported on rigid 5-cm wedges. Participants completed an 8-week supervised bodyweight squat program performed twice weekly, with progressive increases in training volume and intensity. Squats were performed to approximately parallel depth, using a controlled \~2-s eccentric phase followed by maximal intended concentric velocity, with 2-min rest intervals between sets.

Sponsors

Uskudar University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER
Masking
SINGLE (Outcomes Assessor)

Intervention model description

A randomized parallel-group design was used. Participants were randomly assigned to one of two squat exercise groups, and each group performed a different squat modality.

Eligibility

Sex/Gender
FEMALE
Age
18 Years to 35 Years
Healthy volunteers
Yes

Inclusion criteria

* No musculoskeletal, neurological, or cardiopulmonary conditions that would prevent participation in exercise * Healthy young adults * No regular lower extremity training participation in the last 6 months

Exclusion criteria

* History of surgery or serious injury to the knee, hip, or ankle joints within the past year * Presence of any neurological disorder affecting balance or motor control * Presence of any cardiovascular or pulmonary disease that contraindicates exercise participation

Design outcomes

Primary

MeasureTime frameDescription
Muscle Strength (Isomed 2000 Isokinetic Dynamometer)Baseline and 8 weeks post-interventionQuadriceps muscle strength was assessed using a Isomed 2000 isokinetic dynamometer, which is considered a gold-standard method for evaluating muscle performance. Isokinetic testing measures maximal torque produced by the muscle throughout the range of motion at a constant angular velocity, providing reliable data on muscle function. Knee extension strength were evaluated.

Secondary

MeasureTime frameDescription
Assessment of Muscle ThicknessBaseline and 8 weeks post-interventionBefore measurement, participants rested for 20 minutes, and quadriceps muscle thickness was assessed at the midpoint between the anterior superior iliac spine and the superior pole of the patella using B-mode ultrasonography. Anterior thigh muscle thickness was defined as the distance between the superficial fascia of the rectus femoris and the femoral periosteum, representing the combined thickness of the rectus femoris and vastus intermedius.

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Sep 15, 2026