Skin Barrier Function in Women Using UV Nail Lamps

Comparison of Objective Skin Barrier Function Parameters Between Women Who Use and Women Who Do Not Use UV Nail Lamps for Nail Treatments

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT07700186

Enrollment

Registered

2026-07-13

Start date

2026-07-01

Completion date

2027-07-01

Last updated

2026-07-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy Volunteers

Keywords

UV nail lamps, Gel manicure, Skin barrier function, Transepidermal water loss (TEWL), Skin hydration, Erythema

Brief summary

The goal of this observational study is to compare objective parameters of skin barrier function between healthy adult women who regularly use UV lamps during nail treatments and women who do not use UV lamps. The main questions it aims to answer are: * Do women who regularly use UV lamps for nail treatments show differences in skin barrier function compared to women who do not use UV lamps? * Are transepidermal water loss, skin hydration, and erythema associated with regular exposure to UV lamps used for nail treatments? * Does the duration of UV lamp use influence skin barrier function parameters? Researchers will compare women who regularly use UV lamps during nail treatments with women who have natural nails and do not regularly expose their hands to UV lamps. Participants will: * Attend a single study visit. * Complete a short questionnaire regarding nail care habits and duration of UV lamp use. * Undergo non-invasive measurements of skin barrier function on the hands, including transepidermal water loss, skin hydration, and erythema assessments.

Interventions

None listed

Study design

Observational model

CASE_CONTROL

Time perspective

CROSS_SECTIONAL

Eligibility

Sex/Gender

FEMALE

Age

18 Years to 50 Years

Healthy volunteers

Yes

Inclusion criteria

* Healthy adult women (≥18 years of age) * Willing and able to provide written informed consent * Willing to complete the study questionnaire

Exclusion criteria

* Active skin diseases (e.g., psoriasis, vitiligo, or other dermatological conditions) * Allergic contact dermatitis * Pregnancy or breastfeeding * Use of topical or systemic corticosteroids, immunosuppressive drugs, or antihistamines

Design outcomes

Primary

Measure	Time frame	Description
Change in Transepidermal Water Loss (TEWL)	Day 1 (single study visit)	Skin barrier function will be assessed by measuring transepidermal water loss using a Tewameter TM 300 probe. Values will be expressed in g/m²/h
Change in Skin Hydration	Day 1 (single study visit)	Hydration of the stratum corneum will be assessed using a Corneometer CM 825 probe.
Change in Skin Erythema	Day 1 (single study visit)	Skin erythema will be assessed using a Mexameter MX 18 probe.

Countries

Croatia

Contacts

CONTACTJosipa Bukić

jbukic@mefst.hr+385917933753

PRINCIPAL_INVESTIGATORJosipa Bukić

University of Split, School of Medicine

Outcome results