Halitoses
Conditions
Brief summary
This study aims to determine the effect of probiotics and Zn/CHx mouthwashes on plaque accumulation and halitosis in fixed orthodontic patients.
Detailed description
Do probiotics and Zn/CHx mouthwashes have an effect on plaque accumulation and halitosis in fixed orthodontic patients?
Interventions
Probiotic :composed of powerful strain of s.salivarius that preserve innate immune system of the main entry point of the body by taken on a regular basis and establish colonization of the throat and mouth which provide clinical care and support of nose, ear, mouth and throat health and provide fresh breath.
BEHAVIORALZinc chlorhexidine mouth wash
Zinc chlorhexidine mouth wash (Zn/CHX) composed of CHX concentrated 0.025% with Zinc acetate 0.3 %, the low concentration of CHX to maintain optimal efficacy with lower incidence of side effects. Zn /CHX was chosen as the active control due to the fact the mixture of Zn salts with low concentration of CHX have shown superior and sustained intra-oral efficacy in managing intra oral halitosis in randomized clinical tria
Sponsors
Sara M Almshhadany
Study design
Allocation
RANDOMIZED
Intervention model
SEQUENTIAL
Primary purpose
SUPPORTIVE_CARE
Masking
NONE
Intervention model description
randomized double blind parallel groups clinical trial
Eligibility
Sex/Gender
ALL
Age
18 Years to 30 Years
Healthy volunteers
Yes
Inclusion criteria
1. good medical health 2. no systematic disease 3. non consuming drugs known to influence salivary flow, halitosis, or oral microbiota
Exclusion criteria
1. alcohol drinking 2. smokers, pregnant and lactating womens 3. allergy or intolerance to corticosteroid treatment, antibiotic, antimicrobial mouth rinses, oral spray or tongue scraper, anti-inflammatory drugs or probiotics.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Plaque accumulation | 4 month | plaque build up on bracket surfaces was evaluated by using modified bonded bracket index ( mbb index), Each tooth was divided into four areas (incisal, distal, mesial, gingival). Plaque accumulation was classified into the following assessment grades: grade 0-no plaque, grade 1-plaque covered ≤ 1/3 of the tooth surface, grade 2-plaque covered ≤ 2/3 of the tooth surface, grade 3-plaque covered \> 2/3 of the tooth surface. Plaque index (%)= Total of plaque values/ Number of surfaces/ Highest graduation score × 100. |
| Halitosis | 4 month | subjective assessment of halitosis determined by using organoleptic score (OLS) 0 No perceivable odor 1. Weakly perceivable odor 2. Perceivable odor 3. Moderate odor 4. Strong odor 5. Extremely strong odor |
Countries
Iraq
Contacts
CONTACTSara M Almshhadany, assistant professor
Outcome results
None listed