Nailfold Capillaroscopic Changes in Psoriasis

Nailfold Capillaroscopic Changes in Psoriasis and Its Correlation With Disease Severity

Status

Not yet recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT07693595

Enrollment

100

Registered

2026-07-09

Start date

2026-09-01

Completion date

2027-05-01

Last updated

2026-07-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Psoriasis

Brief summary

The goal of this observational study is to evaluate nailfold capillaroscopic changes in patients with psoriasis and to assess their correlation with disease severity. The study will also explore differences in capillaroscopic findings across different clinical types of psoriasis and skin phototypes (Fitzpatrick classification). The study will include patients diagnosed with psoriasis attending dermatology outpatient clinics. Participants will undergo clinical assessment and nailfold capillaroscopy to detect microvascular changes.

Interventions

OTHERNailfold Capillaroscopy

Participants will undergo nailfold capillaroscopy using a USB digital capillaroscope to assess microvascular changes in psoriatic patients. Clinical assessment including PASI score and evaluation of nail involvement will also be performed.

Study design

Observational model

COHORT

Time perspective

CROSS_SECTIONAL

Eligibility

Sex/Gender

ALL

Healthy volunteers

Inclusion criteria

* Patients clinically diagnosed with psoriasis.

Exclusion criteria

* Patients with connective tissue diseases (e.g., systemic sclerosis, SLE) * Diabetes mellitus or peripheral vascular disease * Current smokers * Pregnant or lactating women * Recent use of vasodilators or beta-blockers * Manual workers exposed to vibrating tools

Design outcomes

Primary

Measure	Time frame	Description
Nailfold capillaroscopic abnormalities in psoriasis patients	Baseline	Detection and description of nailfold capillaroscopic (NFC) abnormalities in patients with psoriasis.

Secondary

Measure	Time frame	Description
Variation of nailfold capillaroscopic findings among different clinical types of psoriasis and correlation with disease severity (PASI score).	Baseline	Correlation between PASI score and presence of NFC changes. \- Comparison of nailfold capillaroscopic findings in different types of psoriasis

Countries

Egypt

Contacts

CONTACTAhmed H Nouh, Asst Prof Derm & Venereol

Dr.ahmednouh@azhar.edu.eg+201062034079

CONTACTHadil J Albarrawi

hadeeljamil71@gmail.com+201096205545

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Jul 18, 2026