Type 2 Diabetes Mellitus (T2DM)
Conditions
Keywords
Wearable hip exoskeleton, Bot-Fit, Type 2 diabetes, Postprandial glucose, Glycemic response, Walking
Brief summary
This randomized crossover proof-of-concept study evaluated the effects of walking with a wearable hip exoskeleton on postprandial glycemic and physiological responses in patients with type 2 diabetes. Participants completed four experimental conditions: seated control, walking without the wearable hip exoskeleton, walking with the Bot-Fit device in Aqua mode, and walking with the Bot-Fit device in Boost mode. The primary aim was to determine whether walking with the wearable hip exoskeleton alters postprandial glucose responses compared with seated control and conventional walking conditions in patients with type 2 diabetes.
Detailed description
This study investigated whether walking with a wearable hip exoskeleton could modulate postprandial glycemic and physiological responses in patients with type 2 diabetes. Using a randomized crossover design, each participant completed four experimental conditions in a controlled laboratory setting: seated control, walking without the wearable hip exoskeleton, walking with the Bot-Fit device in Aqua mode, and walking with the Bot-Fit device in Boost mode. Postprandial glucose responses were assessed after meal ingestion during each experimental trial. Physiological responses, including heart rate and perceived exertion, were also evaluated to compare the metabolic and perceptual demands of walking with and without the wearable hip exoskeleton. The study was designed as a proof-of-concept trial to examine whether wearable hip exoskeleton-assisted walking may influence postprandial glucose regulation in patients with type 2 diabetes.
Interventions
DEVICEBot-Fit Aqua Mode
Participants performed 30 minutes of overground walking while wearing the Bot-Fit wearable hip exoskeleton in Aqua mode during the postprandial period.
DEVICEBot-Fit Boost Mode
Participants performed 30 minutes of overground walking while wearing the Bot-Fit wearable hip exoskeleton in Boost mode during the postprandial period.
BEHAVIORALNon-Assisted Walking
Participants performed 30 minutes of overground walking without wearable hip exoskeleton assistance during the postprandial period.
Sponsors
CHA University
Samsung Electronics
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
BASIC_SCIENCE
Masking
NONE
Masking description
The outcomes assessor was masked to the intervention condition during outcome processing and analysis.
Intervention model description
Each participant completed four experimental conditions in a randomized crossover design: seated control, walking without the wearable hip exoskeleton, walking with the Bot-Fit device in Aqua mode, and walking with the Bot-Fit device in Boost mode.
Eligibility
Sex/Gender
ALL
Age
55 Years to 75 Years
Healthy volunteers
No
Inclusion criteria
* Adults diagnosed with type 2 diabetes mellitus. * Participants who were able to complete walking trials with and without the wearable hip exoskeleton. * Participants who provided written informed consent before participation.
Exclusion criteria
* Participants with unstable cardiovascular, neurological, or musculoskeletal conditions that could affect walking ability or safe participation. * Participants with conditions that could interfere with postprandial glucose assessment. * Participants who were unable to safely use the wearable hip exoskeleton. * Participants who were unable to comply with the study procedures.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Incremental Area Under the Curve for Postprandial Glucose | Up to 120 minutes after meal ingestion during each experimental trial | Incremental area under the curve for postprandial glucose was calculated during the postprandial measurement period for each experimental condition. |
Secondary
| Measure | Time frame |
|---|---|
| Peak Postprandial Glucose Concentration | Up to 120 minutes after meal ingestion during each experimental trial |
| Heart Rate Response | Up to 30 minutes |
| Rating of Perceived Exertion | Up to 30 minutes |
Countries
South Korea
Contacts
PRINCIPAL_INVESTIGATORSeung-Bo Park, Ph.D
CHA University
Outcome results
None listed