MCI
Conditions
Brief summary
1. To analyze the therapeutic effects of lavender aromatherapy on memory function and overall cognitive function in older adults with Mild Cognitive Impairment (MCI); 2. To analyze whether lavender aromatherapy improves executive function, language ability, attention, visuospatial ability, anxiety, depression, quality of life, and sleep in older adults with MCI.
Detailed description
The intervention protocol was established as follows: Based on the elderly participant's usual bedtime, the time of going to bed was recorded. The participant was instructed to assume a comfortable sleeping position, use the graduated dropper provided with the essential oil bottle to measure 0.15 ml (approximately 3 drops; theoretically, 0.05 ml per drop) of diluted lavender essential oil, and drip it vertically onto the upper center of a cotton pad. The cotton pad was then pinned to the collar with a safety pin, and the participant was instructed to inhale the scent evenly for 30 minutes. Afterward, the intervention staff or caregiver will remove the cotton pad. The intervention will be conducted 5 days a week for 12 weeks.
Interventions
OTHERaromatherapy
Participants in the intervention group will receive aromatherapy inhalation for 30 minutes per session, five times a week, over a period of 12 week
Sponsors
China Medical University, China
Study design
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Age
60 Years to 95 Years
Healthy volunteers
No
Inclusion criteria
1. The MCI mentioned in this study meets the diagnostic criteria proposed by the \*Chinese Expert Consensus on the Diagnosis and Treatment of Alzheimer's Disease-Derived Mild Cognitive Impairment (2021)\*: cognitive impairment reported by the patient or an informant, or identified by an experienced clinician; objective evidence of impairment in one or more cognitive domains, with episodic memory impairment being the most common; complex instrumental activities of daily living may be mildly impaired, but the ability to perform basic activities of daily living remains independent; the diagnostic criteria for dementia are not met. 2. MoCA-Beijing version scores were adjusted for education level: ≤13 for junior high school education or below, ≤19 for high school education, and ≤24 for university education or above; MMSE score \>24; ADL score \<23. 3. Age between 60 and 79 years. 4. Normal olfactory function assessed using the "Sniffin' Sticks" test. 5. Ability to communicate normally and complete cognitive assessments. 6. Residing in a senior care facility with no plans to leave within the next 12 weeks.
Exclusion criteria
1. Presence of other conditions known to affect cognitive function, such as psychiatric disorders (e.g., schizophrenia, depression). 2. History of asthma or any allergic conditions. 3. Use of any prescription medications that may impact cognitive function (including psychotropic drugs and others)
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Gobal cognitive function | Week 12 | Use the Mini-Mental State Examination to assess overall cognitive function. |
| Memory | Week 12 | Use the Auditory Verbal Learning Test to assess memory function. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Language function | Week 12 | Use the Boston Naming Test to assess Language function |
| Executive function | Week 12 | Use the TMT-B to assess Executive function |
| Visual space | Week 12 | Use the Draw-a-Clock Test to assess Visual space |
| Attention | Week 12 | Use the TMT-A to assess Attention |
| Anxiety | Week 12 | Use the 15-item Geriatric Depression Scale to assess Anxiety |
| Depression | Week 12 | Use the 15-item Geriatric Depression Scale to assess Depression |
| Sleep Quality | Week 12 | Use the Pittsburgh Sleep Quality Index to assess Depression |
| Quality of Life assess | Week 12 | Use the ShortForm 8 Health Survey Questionnaire to assess Depression |
Contacts
CONTACTYuxin Zhang, Graduate
PRINCIPAL_INVESTIGATORYuxin Zhang, Graduate
China Medical University, China
Outcome results
None listed