Clinical Performance of Different Ion-Releasing Restorative Systems in Class II Cavities

Two-Year Clinical Performance of Different Ion-Releasing Restorative Systems Applied in Class II Cavities

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT07688343

Acronym

ION-REST II

Enrollment

Registered

2026-07-07

Start date

2025-06-01

Completion date

2027-07-01

Last updated

2026-07-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dental Caries

Brief summary

Different ion-releasing restorative systems will be applied in class II cavities then their clinical performance will be evaluated and compared

Detailed description

This randomized clinical trial aims to evaluate the clinical performance of different ion-releasing restorative systems used in Class II posterior cavities over a two-year follow-up. Patients must be in adults (not less than 18 years old), able to attend regular follow-up visits, presenting with at least four carious class II posterior teeth requiring restoration. Pregnant patients will be excluded.

Interventions

PROCEDUREconventional bulk fill restorative system

conventional bulk fill restorative system used for posterior applications

PROCEDUREion-releasing restorative system 1

ion-releasing restorative system 1 used for posterior applications

PROCEDUREion-releasing restorative system 2

ion-releasing restorative system 2 used for posterior applications

PROCEDUREion-releasing restorative system 3

ion-releasing restorative system 3 used for posterior applications

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

DOUBLE (Subject, Investigator)

Eligibility

Sex/Gender

ALL

Age

18 Years to 40 Years

Healthy volunteers

Yes

Inclusion criteria

* at least 4 carious posterior teeth

Exclusion criteria

* pregnancy - not able to attend for regular follow-up -smokers or very bad oral hygiene

Design outcomes

Primary

Measure	Time frame	Description
difference between baseline and after two years of evaluation	baseline to two-years	Changes in restoration performance according to the modified Federation Dentaire Internationale (FDI) criteria from baseline to 2 years. Scores range from 1 to 5, where lower scores indicate better clinical performance and higher scores indicate poorer clinical performance.

Countries

Egypt

Contacts

PRINCIPAL_INVESTIGATORAsmaa A Elbanna, Assistant Lecturer

Faculty of Dentistry, Mansoura University

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Jul 10, 2026