Relationship Between Mechanical Ventilator's Modes , Intra-Abdominal Pressure, Mechanical Power and Gastric Tube Tolerance Among Mechanically Ventilated Patients.

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT07687303

Acronym

MV and IAP

Enrollment

Registered

2026-07-07

Start date

2026-08-01

Completion date

2026-11-01

Last updated

2026-07-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Intra Abdominal Pressure, Mechanical Power

Keywords

mechanical ventilator modes, intraabdominal pressure

Brief summary

The study aims to: Explore the relationship between MV modes on the IA, MP and GT tolerance among mechanically ventilated patients.

Detailed description

Modes of MVs by means of their differential effect on intra-thoracic pressure can have a significant influence on IAP. An ideal ventilation mode could optimize respiratory mechanics and may protect a variety of body systems functions. Among the many MV modes, SIMV, BIPAP and CPAP are the three most used modes

Interventions

None listed

Study design

Observational model

OTHER

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 60 Years

Healthy volunteers

Inclusion criteria

* adult patients requiring MV in ICU

Exclusion criteria

* patients with abdominal or chest trauma, * patients with intra abdominal pathologies, * patients who had received more than 10 units of red blood cells or more than 5 liters of intravenous liquids over the last 24 h, * patients with sepsis or hepatic, or renal dysfunction, * patients in positions other than supine, and * body mass index (BMI) ≥ 30 kg/m2.

Design outcomes

Primary

Measure	Time frame	Description
intra-abdominal pressure "IAP"	day 1	IAP will be measured through foly catheter
mechanical power	day 1	it will be: MP (J/ min) =0.098×RR×Vt × \[Peak Pressure-(DP/2)\] measured through folly catheter
gastric tube tolerance	day 1	The GT tolerance will be presented as yes if the patient was on GT feeding, and no, if the patient had delayed gastric emptying and converted to gastric drain

Countries

Egypt

Contacts

CONTACTheba attia lecturer, lecturer

heba.attia@nur.dmu.edu.eg045 01274855242

CONTACTAlaa Mustafa assistant professor, assistant professor

alaa.mustafa@nur.dmu.edu.eg0201097210526

PRINCIPAL_INVESTIGATORsahar youness youness, professor

professor of emergency and critical nursing

Outcome results