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Effect of Lower Extremity Modified Constraint-induced Movement Therapy on Locomotion in Children With Hemiplegia

Effect of Lower Extremity Modified Constraint-induced Movement Therapy on Locomotion in Children With Hemiplegia

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT07686809
Enrollment
30
Registered
2026-07-07
Start date
2026-06-01
Completion date
2026-08-30
Last updated
2026-07-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Spastic Hemiplegic Cerebral Palsy

Brief summary

* To determine the effect of modified constraint-induced movement therapy on spatial and temporal gait parameters in children with hemiplegia. * To determine the effect of modified constraint-induced movement therapy on functional mobility in children with hemiplegia.

Detailed description

Children with spastic hemiplegic cerebral palsy experience longer gait cycles, slower walking speeds, and longer support phases compared to healthy children, with substantial joint angle differences noted during ground contact and stride buffering. Although most can achieve independent walking, they often exhibit poor motor coordination, resulting in short strides and high stride frequencies for speed maintenance. Modified constraint-induced movement therapy has been employed to enhance lower-extremity function, but its effectiveness on key ambulation aspects like gait speed and balance remains unclear. The reliance on the unaffected limb further impacts locomotive behavior, leading to stiff knee gait and reduced functional mobility. This study aims to explore the therapy's effects on locomotion in hemiplegic children.

Interventions

Three tasks will be designed to be performed for 10 min each while using the knee scooter as a method of constraint-induced movement therapy The 3 tasks will be as follows: 1. Walking with knee scooter forward on 8 meter walkway 2. Walking with knee scooter backward on 8 meter walkway 3. Standing with the knee scooter on balance board

OTHERConventional physical therapy

1. Repetitive motor training following shaping task * Step on stool. * Squat to stand. * Pressing the pedal stepper. * Walking on treadmill. * Bicycle. * Air walker. 2. Behavioral strategies: * Walking with picking toys from ground * Passing obstacles * Walking with a ball, moving it by the lower extremity

Sponsors

Cairo University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Subject)

Eligibility

Sex/Gender
ALL
Age
6 Years to 8 Years
Healthy volunteers
No

Inclusion criteria

1. The age of the selected children will range from 6 to 8 years old. 2. Degree of spasticity will range from 1+ to 2 according to the modified Ashworth scale. 3. The level of motor function of the children will be levels I-II according to the Gross Motor Function Classification System. 4. Participants will present a score between 41 to 56 points on the pediatric balance scale. 5. They will be able to follow instructions and understand commands.

Exclusion criteria

1. Bone and tendon lengthening surgeries within the last 6 months. 2. Lung and heart diseases and disorders. 3. Vision or hearing problems. 4. Children with fixed deformities in the lower extremity. 5. Children with epilepsy. 6. Recent intramuscular Botulinum toxin injection.

Design outcomes

Primary

MeasureTime frameDescription
assessment of spatial gait parametersAt baseline and after Four weeksKinovea is a free 2D motion analysis software that facilitates inexpensive, sensor-free video-based motion assessments suitable for clinical practice. Its reliability has been established for measuring cervical range of motion (ROM) in both sagittal and frontal planes, dominant wrist joint ROM, shoulder ROM, and ankle joint ROM during walking. Additionally, it effectively measures spatial gait parameters, including stride length, step length, and hip, knee, and ankle angles at initial contact and mid-swing stages of the gait cycle. Required tools for its use include a walking area, digital camera, adhesive skin marks, and a tripod.

Secondary

MeasureTime frameDescription
assessment of Temporal gait parametersAt baseline and after four weeksKinovea is a free 2D motion analysis software that utilizes inexpensive, sensor-free video-based techniques for clinical motion analysis. Its reliability is essential for assessing important psychometric properties, especially in measuring various range of motion (ROM) for cervical, shoulder, and ankle joints, as well as capturing gait parameters like stance and swing phases. Required tools for its use include a walking area, digital camera, adhesive skin marks, and a tripod.
assessment of the functional mobilityAt baseline and after four weeksThe Gross Motor Function Measure (GMFM-88) is a reliable and valid assessment tool for measuring gross motor function in children with cerebral palsy, specifically focusing on standing (segment D) and walking/running (segment E). It is widely used in clinical and research settings to track changes over time or assess the impact of interventions. Due to its lengthy administration time, it is best used for annual or biannual evaluations or research studies, and testers should be well-versed in its use prior to administration.

Countries

Egypt

Contacts

CONTACTMohamed Ali Taha
dr.mo7amed.ali224@gmail.com01022599920

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Jul 8, 2026