Hemiplegia, Intracranial Hemorrhage, Spontaneous, Stroke
Conditions
Keywords
nerve conduction study, Electrophysiology, Fugl-Meyer Assessment, Rehabilitation
Brief summary
Stroke-related hemiplegia may be accompanied by peripheral nerve conduction abnormalities, which may contribute to motor impairment and functional limitations. However, the frequency of these abnormalities and their relationship with clinical status have not been fully characterized. This single-center observational study aims to evaluate the frequency of peripheral nerve conduction abnormalities identified by nerve conduction studies in patients with unilateral hemiplegia and to examine their association with motor and functional clinical assessment scores. The findings may contribute to a better understanding of peripheral nerve involvement in stroke rehabilitation.
Detailed description
This is a single-center observational study designed to evaluate peripheral nerve conduction abnormalities in patients with unilateral hemiplegia following stroke. Participants undergo standardized nerve conduction studies together with routine clinical assessments, including validated measures of motor recovery and functional status. The study aims to describe the frequency of peripheral nerve conduction abnormalities within the study population and to examine their association with clinical assessment scores. The results may improve the understanding of peripheral nerve involvement in patients with hemiplegia and provide information that may be useful for rehabilitation practice.
Interventions
DIAGNOSTIC_TESTNerve Conduction Study
Standardized motor and sensory nerve conduction studies were performed to evaluate peripheral nerve conduction abnormalities in patients with unilateral post-stroke hemiplegia. The test was used as a diagnostic assessment and was not part of a therapeutic intervention.
Sponsors
Baskent University
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Adults (≥18 years of age). * Unilateral hemiplegia secondary to ischemic or hemorrhagic stroke, or intracranial hemorrhage. * Ability to undergo standardized nerve conduction studies and clinical assessments. * Provision of written informed consent.
Exclusion criteria
* Bilateral hemiplegia. * Hemiplegia secondary to benign or malignant intracranial tumors. * Upper or lower extremity fracture, amputation, skin lesions preventing electrophysiological testing, or diagnosed peripheral vascular disease. * Concomitant neurological disorders that may affect motor function or peripheral nerve conduction (e.g., Parkinson's disease, multiple sclerosis, encephalitis). * Contraindications to nerve conduction studies (e.g., cardiac pacemaker or inability to safely undergo the examination). * Inability to cooperate with or tolerate nerve conduction studies.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Association Between Peripheral Nerve Conduction Abnormalities and Clinical Assessment Scores | Baseline | To evaluate the association between peripheral nerve conduction abnormalities identified by standardized nerve conduction studies and motor and functional outcome measures in patients with unilateral hemiplegia secondary to ischemic or hemorrhagic stroke. The frequency of peripheral nerve conduction abnormalities within the study population will also be described. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Fugl-Meyer Assessment (FMA) Score (Upper and Lower Extremities) | Baseline | Association between peripheral nerve conduction abnormalities and motor impairment assessed using the Fugl-Meyer Assessment. |
| Functional Independence Measure (FIM) Score | Baseline | Association between peripheral nerve conduction abnormalities and functional independence measured using the Functional Independence Measure. |
| Timed Up and Go Test (TUG) | Baseline | Association between peripheral nerve conduction abnormalities and mobility performance assessed using the Timed Up and Go test. |
Countries
Turkey (Türkiye)
Outcome results
None listed