The Impact of Good Versus Poor Sleep Quality on Quality of Life, Depression, and Fatigue in Individuals With Multiple Sclerosis

Multiple Sklerozlu Bireylerde Iyi Uyku Kalitesi ve kötü Uyku Kalitesinin yaşam Kalitesi, Depresyon ve Yorgunluk üzerine Etkisi

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT07681037

Enrollment

121

Registered

2026-07-02

Start date

2025-07-15

Completion date

2026-01-05

Last updated

2026-07-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Depression, Multiple Sclerosis, Quality of Life

Keywords

Fatigue, Depression, Quality of life, Multiple Sclerosis, Sleep Quality

Brief summary

This cross-sectional study was conducted to examine the effects of good and poor sleep quality on quality of life, depression, and fatigue in individuals with multiple sclerosis. The study was conducted at the Multiple Sclerosis (n=121) Outpatient Clinic of the Health Research and Application Center at the Trakya University between July 15, 2025, and December 30, 2025, with patients who were receiving outpatient treatment, had no communication difficulties, and agreed to participate in the study. These patients were provided with an "Informed Consent Form" "Pittsburgh Sleep Quality Index," "SF-12 Quality of Life Scale," "Beck Depression Scale," and "Fatigue Impact Scale." Participants were informed about the purpose of the study, and if they agreed to participate, they were asked to complete the questionnaire forms.

Detailed description

Sleep disorders are common among individuals with multiple sclerosis and negatively impact their physical and psychological well-being. This study was conducted to examine the effects of good and poor sleep quality on quality of life, depression, and fatigue in individuals with multiple sclerosis. Material and Methods: The study was conducted between july 15, 2025 and December 30, 2025 with 121 patients diagnosed with Multiple Sclerosis at the Neurology outpatient clinic of a university hospital in Edirne. Data were collected using "Patient Information Form" "Pittsburgh Sleep Quality Index," "SF-12 Quality of Life Scale," "Beck Depression Scale," and "Fatigue Impact Scale." Participants were informed about the purpose of the study, and if they agreed to participate, they were asked to complete the questionnaire forms. Financial Support: The present study was supported by the Research Fund of Trakya University. Project No: 2025/278

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 80 Years

Healthy volunteers

Inclusion criteria

* Being over 18 years of age * Having a confirmed diagnosis of multiple sclerosis * Being a registered patient at a multiple sclerosis clinic * Not experiencing communication difficulties * Volunteering to participate in the study

Exclusion criteria

* Being under 18 years of age * Not having a confirmed diagnosis of multiple sclerosis * Not currently attending a multiple sclerosis clinic * Experiencing communication difficulties * Not volunteering to participate in the study

Design outcomes

Primary

Measure	Time frame	Description
determining sleep quality	6 month	To evaluate the association between sleep quality and quality of life, depression, and fatigue in individuals with multiple sclerosis.

Countries

Turkey (Türkiye)

Contacts

PRINCIPAL_INVESTIGATORAyfer Gunes

Trakya University Medical Research and Application Centre, Department of Neurology

Outcome results