Closed Sinus Lifting Using Xenograft With or Without Liposomal Apigenin-Loaded Scaffold

Clinical and Radiographic Evaluation of Closed Sinus Lifting Using Xenograft With or Without Liposomal Apigenin-Loaded Scaffold : A Randomized Controlled Clinical Study

Status

Enrolling by invitation

Phases

Unknown

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT07678749

Enrollment

Registered

2026-07-01

Start date

2025-11-05

Completion date

2026-12-01

Last updated

2026-07-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Apigenin Loaded Scaffold, Closed Sinus Lift

Brief summary

aims to evaluate the effectiveness of closed sinus lifting using xenograft with or without a liposomal Apigenin-loaded scaffold in the posterior maxilla.

Interventions

PROCEDUREsinus lifting

closed sinus lifting using xenograft + liposomal Apigenin-loaded scaffold, followed by implant placement.

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

DOUBLE (Subject, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

18 Years to 50 Years

Healthy volunteers

Yes

Inclusion criteria

* 1\. Partially edentulous patients with a maxillary posterior edentulous ridge for more than 4 months after extraction. 2\. Both males and females. 3. Adults aged between 18-50 years. 4. Systemically healthy individuals. 5\. Residual alveolar ridge height ranging from 4 to 6 mm (measured by preoperative CBCT) 6. No previous surgical or radiation treatment involving the maxillary sinus.

Exclusion criteria

Design outcomes

Primary

Measure	Time frame
1. Bone height ( Apical Bone Height Gain ): Measured from first implant thread to sinus floor.	6 months

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Jul 2, 2026