Skip to content

Mulligan Mobilization Versus PNF Technique in SIS

Shoulder Mulligan Mobilization Versus Proprioceptive Neuromuscular Facilitation Technique In Subacromial Impingement Syndrome

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT07675655
Enrollment
69
Registered
2026-06-30
Start date
2025-09-02
Completion date
2026-08-01
Last updated
2026-06-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Subacromial Impingement Syndrome

Keywords

Rotator Cuff Impingement Syndrome, PROPRIOCEPTIVE NEUROMUSCLAR FACILITATION TECHNIQUE, mulligan mobilization

Brief summary

To investigate the differences between adding Mulligan mobilization and PNF to the conventional physical therapy program on shoulder pain, function, shoulder muscles strength, glenohumeral flexion, abduction, external rotation, and internal rotation ROM, scapular symmetry, and pectoralis minor length in patients with SIS.

Detailed description

i need brief summery with same means Shoulder pain affects 4.7%-46.7% of adults annually and is the third most common musculoskeletal complaint. It accounts for 13% of sick leaves and $7 billion in healthcare costs, posing a significant economic and societal burden. SIS is the leading cause of shoulder pain and overhead reach limitation, accounting for 44-65% of cases. SIS space narrowing has two causes: intrinsic impingement (tendon degeneration from overuse, tension overload, or trauma) and extrinsic impingement (tendon inflammation from mechanical compression by an external structure). Extrinsic factors contributing to SIS include poor posture, altered scapular or GH kinematics, posterior capsular tightness, and acromial pathology. Research demonstrates that SIS patients show restricted GH external rotation and increased humeral head translation, leading to subacromial space narrowing and tissue compression. the scapula exhibits a pattern of posterior tilting, external rotation, and upward rotation during GH elevation. Patients show altered scapular kinematics that include decreased upward rotation and increased anterior tilting and internal rotation. rotation. The scapular muscle plays a crucial function in stabilizing the scapula, to maintain the base of the GH during motion. The upper trapezius (UT), lower trapezius (LT) and serratus anterior (SA) function as a force couple to induce scapular upward rotation, allowing the tissues beneath the coracoacromial arch to move freely. In individuals with SIS, SA activity is reduced, whereas UT and LT activity is elevated. Maintaining proper scapulohumeral rhythm is essential, particularly in the mid-range of arm elevation, to prevent subacromial impingement. The treatment approach for SIS are corticosteroid injections, nonsteroidal anti-inflammatory medications, electrotherapy treatments, manual techniques like joint mobilization, proprioceptive neuromuscular facilitation (PNF) exercises, progressive resistive exercises, taping, and stabilisation exercises. PNF is a therapeutic exercise method that enhances neuromuscular control and motor response. Adding PNF to conventional physiotherapy significantly improves pain and function compared to conventional treatment only. Also, Adding PNF to conventional program enhances early ROM gains in SIS treatment and sustain improvements post-treatment. In the manual therapy approach known as Mobilization with Movement (MWM), which was created by Brian Mulligan, the therapist applies a specially directed glide to a painful joint as the patient actively moves that same joint. The fundamental idea of MWM is to identify and correct joint positional faults caused by soft or bony tissue lesions around the joint. Four sessions of MWM significantly improve pain, pain-free shoulder flexion, maximal flexion, and external rotation in SIS patients. To the authors' knowledge, none of the studies have investigated the differences between integrating Mulligan mobilization and PNF to the conventional physical therapy program to achieve better outcomes.

Interventions

OTHERStandard conventional program

Patients receive standard conventional program inform of exercise and TENS

OTHERProprioceptive neuromuscular facilitation (PNF) +Standard program

patients receive Proprioceptive neuromuscular facilitation (PNF) +Standard conventionalprogram

OTHERMWM +Standard program

patients receive MWM +Standard program

Sponsors

Cairo University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Outcomes Assessor)

Intervention model description

Group A: will receive a program of conventional exercise include strengthening for scapular stabilizers, Posterior shoulder stretching exercises (PSSEs) (modified cross-body stretch and modified sleeper stretch), stretching for pectoralis minor and transcutaneous electrical nerve stimulation (TENS). Group B : will receive PNF diagonal pattern exercise program in addition to conventional Exercise as in group A. Group C : will receive a posterolateral MWM in addition to conventional Exercise as in group A.

Eligibility

Sex/Gender
ALL
Age
20 Years to 40 Years
Healthy volunteers
No

Inclusion criteria

1. Sixty nine Males and females subjects with SIS, age between 20-40 years old and body mass index (BMI) 18-27.9 kg/m2 2. The SIS group will be limited to patients who had history of shoulder pain of \>1-week duration. 3. Pain localized at the proximal anterolateral shoulder region. 4. Patients with subacromial pain syndrome with positive results of 3 of 5 tests: painful arc, pain or weakness with resisted external rotation, Neer test, Hawkins Kennedy test, and Jobe/empty can test.

Exclusion criteria

* Patients will be excluded if they had any of the following conditions: 1. Open wounds, infection, acute injuries, swelling, rheumatoid arthritis, reflex sympathetic syndrome, or adhesive capsulitis. 2. BMI greater than 28 kg/m². 3. History of shoulder girdle fractures and dislocation, shoulder surgery in the last 12 months or full thickness rotator cuff tear. 4. History of systemic or neurological disorder, cervical radiculopathy and subjects who had received physical therapy treatment for their shoulder within the past three months. 5. History of corticosteroid injection in the shoulder region less than 12 weeks previously.

Design outcomes

Primary

MeasureTime frameDescription
The Shoulder Pain and Disability Index (SPADI)at baseline and after 6 weeks post interventionassesses pain and disability in shoulder pathology. Patients answer five questions related to pain and eight questions related to function
Shoulder ROMat baseline and after 6 weeks post interventionthe smartphone inclinometer will be used to perform clinical measurements of shoulder motion (Flexion, Abduction, External Rotation in 90- of Abduction, Internal Rotation in 90- of Abduction)
The Timed Functional Arm and Shoulder Test (TFAST)at baseline and after 6 weeks post-interventionTask 1: Hand to Head and Back (HHB) 30s Movement: Move arm from the side to touch the back of the head (palm preferred), then move down to touch the small of the back with the back of the hand. Scoring: 1 rep per head touch. Task 2: Wall Wash (Inward/Outward) 60s per direction Movement: Move a towel in a 12-inch diameter circle at shoulder height, touching 4 drawn marks. Start at the top mark. Scoring: 1 rep each time the hand passes the top mark. Done clockwise and counter-clockwise. Task 3: Gallon-Jug Lift - 30s Movement: Lift a 3.78 kg jug from a 36-inch high counter to lightly tap a shelf 20 inches above it, then lower it without resting. Scoring: 1 rep per shelf tap. Total TFAST Score Calculation To equalize all tasks for a 30-second timeframe, the final score is calculated using this formula: \[HHB + (wall wash inward and outward/4) + gallon-jug lift\]

Secondary

MeasureTime frameDescription
Measuring isometric strength with Hand-held sphygmomanometerat baseline and after 6 weeks post-interventionA Hand-held sphygmomanometer (HHS) will been more commonly used to measure Internal and External rotation and shoulder scaption isometric strength
The Modified Lateral Scapular Slide testat baseline and after 6 weeks post-interventionShoulder position will be visually estimated, and the distance from the inferior angle of the scapulae and the spinous process of T7 .will be measured using a tape measure or goniometer in 3 different arm positions: neutral, 45°, and 90° The first position was with the arms by the side. The second was with the subject's hands on the hips, and the third was with the arms elevated to 90° of shoulder abduction in scaption with maximal internal rotation and 1 kg load hold in their hands
Pectoralis minor length testat baseline and after 6 weeks post-interventionSubjects will lie supine, relaxed, with legs bent and arms at their sides in neutral rotation. An investigator will measure the vertical distance from the posterolateral acromion to the table in millimeters using a metal scale. A positive test, indicating pectoralis minor tightness, is defined as a distance greater than 2.54 cm (1 inch), while a negative test is a measurement less than or equal to 2.6 cm

Countries

Egypt

Contacts

CONTACTMina Magdy, Master
mina.magdy.9595@gmail.com01277660470
CONTACTMarihan zakaria, Lecturer
marihan_aziz@cu.edu.eg01201227971

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Jul 1, 2026