Healthy Adult Participants
Conditions
Keywords
Healthy, canola, surfactant, green tea
Brief summary
The objectives of the study were to investigate effects of foods prepared in palm oil blended with canola oil containing surfactants and green tea extract on postprandial triglyceride levels in healthy volunteers. There were 22 subjects in the study. They were divided into 2 groups: 1.comsumed foods fried in palm oil blended with canola oil containing surfactants and green tea extract and 2.comsumed foods fried in palm oil. Postprandial triglyceride, lipid profiles, and liver and kidney functions were evaluated before and after taking 5 hours.
Interventions
OTHERFried Foods Prepared in Palm Oil Blended With Canola Oil Containing Surfactants and Green Tea Extract
Take fried foods prepared in palm oil blended with canola oil containing surfactants and green tea extract 7 pieces.
OTHERFried Foods Prepared in Palm Oil
Take fried foods prepared in palm oil 7 pieces.
Sponsors
Chulalongkorn University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
TRIPLE (Subject, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to 60 Years
Healthy volunteers
Yes
Inclusion criteria
* Male or female participants aged 18-60 years. * Participants with fasting triglyceride levels \<150 mg/dL (after fasting for at least 8-12 hours before blood collection). * Participants without a history of cardiovascular disease, diabetes mellitus, thyroid disease, cancer, liver disease, or kidney disease. * Participants who are able to read and write. * Participants who voluntarily agree to participate after receiving information regarding the study objectives, procedures, potential risks, and expected benefits; are able to comply with the study protocol; and provide written informed consent.
Exclusion criteria
* Participants with a history of allergy or adverse reactions, such as skin, respiratory, or gastrointestinal symptoms, after consuming foods containing canola oil, polyglycerol esters of fatty acids (PGEs), green tea extract, palm oil, or banana. * Participants who have consumed medications, dietary supplements, herbal products, or foods that may affect metabolism, such as weight-loss products or L-carnitine, within 2 weeks prior to enrollment. * Participants who regularly use medications that may affect lipid metabolism or blood lipid levels, such as corticosteroids or lipid-lowering agents. * Participants with serious underlying diseases or poorly controlled medical conditions, such as cancer, cardiovascular disease, or immunodeficiency disorders. * Participants with impaired liver or kidney function, defined as AST/ALT levels \>3 times the upper limit of normal or kidney disease with an estimated glomerular filtration rate (eGFR) \<60 mL/min/1.73 m². * Female participants who are pregnant or breastfeeding. * Participants who regularly smoke. * Participants who regularly consume alcohol. * Participants who are currently participating in another research study.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Postprandial triglyceride | 5 hours | Postprandial triglyceride in blood |
Secondary
| Measure | Time frame |
|---|---|
| Total cholesterol in blood | 5 hours |
| High Density Lipoprotein in blood | 5 hours |
| Low Density Lipoprotein in blood | 5 hours |
| Fasting blood glucose | 5 hours |
| Creatinine in blood | 5 hours |
| Blood Urea Nitrogen | 5 hours |
| Aspartate Aminotransferase in blood | 5 hours |
| Alanine Aminotransferase in blood | 5 hours |
| Alkaline Phosphatase in blood | 5 hours |
| Plasma antioxidant | 5 hours |
Countries
Thailand
Outcome results
None listed