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Comparison of the Efficacy of Conventional Versus Minimally Invasive Non-Surgical Periodontal Therapy in Periodontitis Patients

Comparison of the Efficacy of Conventional Versus Minimally Invasive Non-Surgical Periodontal Therapy in Periodontitis Patients (Randomized Controlled Clinical Trial)

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT07671274
Enrollment
30
Registered
2026-06-26
Start date
2025-08-05
Completion date
2026-08-05
Last updated
2026-06-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Periodontal Disease, Stage III Periodontitis

Keywords

periodontitis, stage III, mechanical debridement

Brief summary

the aim of this study is to investigate the clinical outcomes of Minimally Invasive Non-Surgical Therapy(MINST) compared to Conventional non-surgical periodontal therapy (CNST)

Detailed description

A total of thirty patients were included in the study, Inclusion Criteria: - * Patients with stage III pericdontitis, according to the American Academy of Periodontology (AAP) and the European Federation of Periodontology (EFP) periodontal classification system . * Medically free patients. * Non-smokers * Patients with good oral hygiene. Exclusion Criteria: - * Pregnant or lactating females. * Patients with systemic diseases that might affect periodontal health * previous periodontal treatment within 6 months before baseline examination. * prior antibiotic regimen use within 1 month before baseline examination All participants will receive oral hygiene instructions including toothbrushin, interdental cleaning, and plaque control behavior reinforcement with oral hygiene self-care regimens to be followed at home. * On the conventional non-surgical periodontal therapy side, a power-driven piezo•electric ultrasonic scaling device with scaling tips will be used the majority of the time to debride subgingival biofilm and calculus. and manual standard gracey curette instruments will be used to refine residuals from root surfaces. * Conversely, the treatment protocol of the minimally invasive non-surgical periodontal therapy side will be followed as in the previous study (5). * Briefly. the root surface of teeth will be thoroughly debrided by a minimally invasive approach using specific thin and delicate piezo-electric scaling tips (Woodpecker � Tip P3. Am Perfect sp. z o .• � Poland) and manual miniature periodontal curettes {� Dent Solutions. Cairo. Egypt) for reducing periodontal tissue trauma. Adjunctive use of magnification loupes will be performed. * Both modalities will be performed under local anesthesia. * All patients will be recalled 1 and 3 months after tre.alment for re-ev.almtion and professional supra-gingival plaque control study parameters are plaque index bleeding of probing periodontal pocket depth clinical attachment loss gingival index

Interventions

On the conventional non-surgical periodontal therapy side, a power-driven piezo•electric ultrasonic scaling device with scaling tips will be used the majority of the time to debride subgingival biofilm and calculus. and manual standard gracey curette instruments will be used to refine residuals from root surfaces.

DEVICEminimally invasive mechanical debridement

Briefly. the root surface of teeth will be thoroughly debrided by a minimally invasive approach using specific thin and delicate piezo-electric scaling tips (Woodpecker � Tip P3. Am Perfect sp. z o .• � Poland) and manual miniature periodontal curettes {� Dent Solutions. Cairo. Egypt) for reducing periodontal tissue trauma. Adjunctive use of magnification loupes will be performed.

Sponsors

Mansoura University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Outcomes Assessor)

Eligibility

Sex/Gender
ALL
Age
20 Years to 40 Years
Healthy volunteers
Yes

Inclusion criteria

* • Patients with stage III pericdontitis, according to the American Academy of Periodontology (AAP) and the European Federation of Periodontology (EFP) periodontal classification system . * Medically free patients. * Non-smokers * Patients with good oral hygiene.

Exclusion criteria

* Pregnant or lactating females. * Patients with systemic diseases that might affect periodontal health * previous periodontal treatment within 6 months before baseline examination. * prior antibiotic regimen use within 1 month before baseline examination

Design outcomes

Primary

MeasureTime frameDescription
Plaque index (PI)basline, 1 month , 3 months1\. Plaque index (PI):The index assigns a score to each tooth based on the amount of plaque present. 0: No plaque is visible. 1. A thin film of plaque is present at the gingival margin (gumline) and can be detected with a probe. 2. Visible plaque along the gingival margin. 3. Heavy plaque accumulation in the gingival margin and interdental spaces.
Bleeding on probing (BOP):baseline, 1 month , 3 months): "0" if no bleeding occurred within 10 second, and "1" if there was bleeding within 10 second.
Probing pocket Depth (PPD)baseline , 1 month , 3 month): will be measured from the gingival margin to the base of the periodontal pocket.
Clinical Attachment Level (CAL)baseline ,1 month , 3 monthwill be measured from the cement-enamel junction to the base of the periodontal pocket.

Countries

Egypt

Contacts

CONTACTfatma saad elsherbini, phd
elsherbinifatma@mans.edu.eg+201128065677

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Jun 27, 2026