Knee Arthritis Osteoarthritis
Conditions
Brief summary
This randomized controlled trial aims to compare the effectiveness of laser therapy and iontophoresis in patients with knee osteoarthritis. The study will evaluate pain reduction, functional improvement, and knee joint mobility following
Detailed description
Participants will be randomly assigned into three groups receiving either laser therapy plus conventional physiotherapy, iontophoresis plus conventional physiotherapy, or conventional physiotherapy alone. Outcome measures will be assessed before and after treatment
Interventions
DEVICELow-Level Laser Therapy
Low-level laser therapy combined with conventional physical therapy for patients with knee osteoarthritis to reduce pain and improve functional mobility and knee joint range of motion
DEVICEIontophoresis
Iontophoresis using dexamethasone combined with conventional physical therapy for patients with knee osteoarthritis to reduce pain and improve physical function and knee joint mobility
Conventional physical therapy program for patients with knee osteoarthritis including therapeutic exercises, stretching, strengthening exercises, and pain relief modalities to improve knee function and mobility.
Sponsors
Kafrelsheikh University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
45 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
* \* Age 45-65 years. * Diagnosed primary knee osteoarthritis (Grade I-II). * Both genders. * Ability to follow treatment protocol.
Exclusion criteria
* \* Previous knee surgery. * Intra-articular injections within last 6 months. * Pacemaker. * Skin lesions at treatment area. * Severe neurological or cardiovascular disorders.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain intensity measured using Visual Analogue Scale (VAS) | Baseline and after 4 weeks of treatment |
| Functional disability measured using WOMAC. | Baseline and after 4 weeks of treatment |
| 3. Knee Range of Motion (ROM). | Baseline and after 4 weeks of treatment |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Change in physical function assessed by the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) Physical Function Subscale | Baseline (Day 0) and Week 4 | The WOMAC Physical Function Subscale consists of 17 items assessing difficulty in performing daily activities. Scores range from 0 to 68, with higher scores indicating worse physical function. |
| 2. Reduction of joint stiffness. | Baseline and after 4 weeks of treatment | — |
| Change in daily activities performance assessed by the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) Physical Function Subscale | Baseline (Day 0) and Week 4 | The WOMAC Physical Function Subscale consists of 17 items assessing difficulty in activities of daily living. Scores range from 0 to 68, with higher scores indicating worse functional limitation. |
Contacts
CONTACTabdulaziz fahad alsulaimani, MASTER
STUDY_CHAIRhane mohamed hamed, PHD
professor of orthopedic surgery depaetment of orthopedic surgery faculty of medicine kafrelsheikh university
STUDY_CHAIRmahmoud mohamed ewida, PHD
professor of basic sciences for physical therapy department of basic sciences for physical therapy faculty oh physical therapy kafrelsheikh university
Outcome results
None listed