Esthetic Zone, Omega-3 Fatty Acids, Socket Preservation
Conditions
Keywords
Omega-3, Socket preservation, Atraumatic extraction, Esthetic zone, Extraction socket, Implant
Brief summary
To evaluate the effect of Omega-3 in preserving bone after extraction
Detailed description
The evaluation of the effect of omega-3 on the bone of the socket with changes in the dimensions like vertical and horizontal bone changes 3months after extraction .
Interventions
DIETARY_SUPPLEMENTOmega 3 Fish Oil supplements
omega-3 fatty acid supplement
Sponsors
Cairo University
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
PREVENTION
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
1. Patients with non-restorable remaining roots. 2. Patients free of systemic conditions that might affect the surgical procedure or the quantity or quality of bone (uncontrolled hypertension, uncontrolled diabetes).
Exclusion criteria
1. Patients below 18 years old 2. Patients with hypersensitivity to omega-3, drug formulations or allergic to seafood. 3. Pregnant or lactating females 4. Patients undergoing chemotherapy or radiotherapy 5. Smokers
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Post-operative pain | immediately after extraction and the second day after extraction | Visual Analogue Scale score "VAS score" From 0-10 scores score 0 is no pain which is the best 1-4 is mild pain 5 is moderate pain from 5 -10 pain is getting worse and 10 is the worst |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Radiographic bone changes "horizontal bone changes " using Cone beam CBCT | before extraction and 3months after omega 3 placement | Performing one CBCT before extraction and one new CBCT after 3 months of extraction and omega-3 placement then comparing both CBCTs by J image computer program to get the difference in vertical bone measurements in millimeter |
| Radiographic bone changes " Vertical bone fill" using CBCT | before and after 3 months of extraction and omega-3 placement | Performing one CBCT before extraction and one new CBCT after 3 months of extraction and omega-3 placement then comparing both CBCTs by J image computer program to get the difference in vertical bone measurements in millimeter |
| Radiographic bone changes "Bone density" using CBCT | 3 months after extraction and placement of omega-3 | Performing one CBCT before extraction and one new CBCT after 3 months of extraction and omega-3 placement then comparing both CBCTs by J image computer program to get the radiographic bone changes in millimeter and Hounsfield units |
| Histological examination | after 3months of extraction during implant placement bone is taken using trephine bur | using Hematoxylin and Eosin staining to measure the area of newly formed bone "Percentage" |
| Healing Index "HI" by Landry et al using scores | after 3months of omega 3 placement | Using Landry et al wound healing index to measure soft tissue reaction changes. Each category is scored from 1 to 5, with 1 indicating very poor healing and 5 indicating excellent healing. The HI is a useful tool for assessing the quality of wound healing and guiding postoperative interventions. |
Countries
Egypt
Outcome results
None listed