Knee Osteoarthritis
Conditions
Brief summary
The project will evaluate the effectiveness of Cryoneurolysis versus radiofrequency procedures in adult patients who are resistant to traditional treatment for knee pain. They are a drug-free pain management procedure.
Detailed description
The main approach to OA management is pain control. Cryoneurolysis versus radiofrequency in decreasing knee pain.
Interventions
DEVICECryoneurolysis
Cryoneurolysis freezes nerves
DEVICEpulsed radiofrequency (RF)
radiofrequency (RF) uses electric pulses
DEVICEcooled radiofrequency
uses cooled radiofrequency energy to deactivate pain-causing nerves
Sponsors
Tanta University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
TRIPLE (Subject, Caregiver, Investigator)
Masking description
This is a prospective, randomised study. The closed envelop randomization method will be used for the randomization of the patients who will be also blinded to group allocation.
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
1. adults between the ages of 30 and 70 years with a clinical diagnosis of refractory knee OA who suffered from knee pain. 2. Patients who cannot afford intra-articular injections. 3. patients who had failed 2 different oral pain medications, and 6 weeks of physical therapy.
Exclusion criteria
1. Patients with OA show improvement in pain after physiotherapy. 2. patients evaluated by an orthopedic surgeon and deemed to be surgical candidates due to knee pathologies other than OA. 3. pregnant patients. 4. patients on anticoagulation therapy, who were not permitted to stop anticoagulation. 5. patients with previous trauma, neurological or endocrine diseases like diabetes mellitus, and knee tumors; and patients with inflammatory arthritis. 6. people who had received an intra-articular knee injection within the last 6 months. 7. Patients with tendon tears, bursitis, or calcified tendonitis as proven by imaging.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change in visual analogue scale after intervention | immediately after intervention | Decrement (clinical improvement) in visual analogue scale (VAS) immediately after intervention. The participant's knee discomfort was measured using a VAS. Participants were asked to score their level of pain on a 100-mm horizontal line, ranging from 0 to 100. |
Countries
Egypt
Contacts
CONTACTAliaa Mamdouh Abdelaziz Farag, MD
Outcome results
None listed