Parkinson Disease (PD)
Conditions
Keywords
Music therapy, Exercise, Motivation, Parkinson's, Neurodegeneration
Brief summary
The purpose of this pilot study is to identify the effects of active versus passive music therapy on functional ability and psychophysiological responses to goal-directed exercise in people with Parkinson's disease.
Detailed description
Using a crossover counterbalanced approach, participants with idiopathic PD (n=28) will be recruited to complete 3 separate experimental visits each with a differing condition: 1) No music (control; CON), 2) PMT, 3) AMT. For each condition, participants will complete a battery of functional testing (sit-to-stand test; STS) and goal-based exercise (6-minute walk test; 6MWT) separated by 20-minutes of rest. Functional ability will be determined via biomechanical parameters (i.e. peak force, braking force, rate of force development) during the 5-time STS test. Exercise capacity (i.e. distance, average walking velocity) will be determined for goal-based exercise during the 6MWT. During each test, a medical grade smartwatch will record psychophysiological (i.e. heart rate, metabolic equivalents, electrodermal activity) responses. Furthermore, psychometric testing for motivation, enjoyment, psychological arousal, fatigue, and rating of perceived exertion will be conducted after each test attempt.
Interventions
BEHAVIORALPassive music therapy
Listening to self-selected music
BEHAVIORALActive music therapy
Structured music therapy with a licensed music therapist
Sponsors
University of Alabama at Birmingham
Rooted Music Therapy
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
50 Years to 89 Years
Healthy volunteers
No
Inclusion criteria
* Formal diagnosis of idiopathic PD * Hoen \& Yahr Stage \<III * Middle or old age onset of PD (at least 50 years of age) * The ability to ambulate without assistive devices * Stable medication regimen for four weeks prior to participation * No changes to treatment of PD in the last month.
Exclusion criteria
* Primary psychiatric disease (non-PD related) * Reports of falling in the last six weeks * Any reason a participant or their healthcare team believed their participation in the study could negatively impact their well-being.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Average time sit to stand | Week 1, Week 2 | Time to complete 5 sit to stand test |
| Total walking distance accumulated in 6 minutes | Week 1, Week 2 | Total distance in meters accumulated during a six minute walk test |
| Total motivation level | Week 1, Week 2 | Motivation levels as assessed by a visual analog scale on 0 to 100 where 0 equals the absence of motivation and 100 indicates extremely motivated |
Countries
United States
Contacts
CONTACTChristopher G Ballmann, PhD
PRINCIPAL_INVESTIGATORChristopher G Ballmann, PhD
University of Alabama at Birmingham
Outcome results
None listed