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Study on the Effect of Edible Mastication Training Colloid Intervention of Oral Muscle Training in Patients of Sarcopenia

Study on the Effect of Edible Mastication Training Colloid Intervention of Oral Muscle Training in Patients of Sarcopenia

Status
Completed
Phases
Unknown
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT07658599
Acronym
EMTC-Sarc
Enrollment
68
Registered
2026-06-22
Start date
2024-03-01
Completion date
2024-04-25
Last updated
2026-06-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Non-sarcopenic Subjects, Possible Sarcopenia, Sarcopenia (With Low ASM by BIM)

Keywords

sarcopenia, chewing, oral strength training, muscle strength

Brief summary

The main purpose of this study is to screen middle-aged and elderly (≧ 45 years old) individuals at high risk of sarcopenia and sarcopenia, and to investigate whether sarcopenia can improve dental bite force and tongue pressure in middle-aged and elderly sarcopenia subjects when given edible chewing training colloidal intervention.This trial method will recruit 120 subjects for oral strength training twice a day for 8 weeks, and compare the difference in chewing level between the subjects using the oral strength training intervention and the oral strength training intervention before and after the test. The differences between dental occlusal force and tongue pressure after training were also explored. The experiment mainly evaluated the scales related to dental occlusal force, tongue pressure, and quality of life, because the quality of oral muscles is highly correlated with the diet and lifestyle of the elderly, and also affects the physical health and mobility of the elderly. Although the loss of muscle mass due to aging may be unavoidable, appropriate oral strength training intervention may delay or modify the adverse effects of sarcopenia and improve quality of life in sarcopenia subjects.

Interventions

BEHAVIORALoral muscle strength training

Oral muscle strength tests are conducted the day before the intervention and during the eighth week after the intervention.

Sponsors

Chang Gung University of Science and Technology
Lead SponsorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
BASIC_SCIENCE
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
45 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

* 45 years old (inclusive) or older * The general public or the institution has stayed for more than 3 months (inclusive) * Those who accept the experimental design and intervention, and are willing to sign the consent form * The source of the diet is that you can eat by mouth independently * Those who meet the diagnosis definition of sarcopenia by the Asian Sarcopenia Consensus Association * No history of chewing and swallowing

Exclusion criteria

* Those who may have allergic or uncomfortable reactions to edible chewing colloids (honey flavor) * Feeders * Other dietitians who cannot complete this researcher * Those who cause discomfort when chewing (such as temporomandibular joint pain, oral ulcers, severe tooth decay, etc.) * Those who report choking and coughing when chewing

Design outcomes

Primary

MeasureTime frameDescription
Based on the results of empirical research on sarcopenia in Asian countries, a diagnostic consensus was established.From Intervention to Experiment Completion (eight weeks)* The cut-off point for abnormal grip strength is less than 28 kg for men and less than 18 kg for women * 6-meter walking speed less than 1.0 second/meter * 5-time chair stand test greater than or equal to 12 seconds * Short physical performance battery, SPPB greater than or equal to 9 points

Countries

Taiwan

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Jun 23, 2026