Myocardial Ischemia
Conditions
Keywords
Ischemia with No Obstructive Coronary Arteries
Brief summary
The aim of this prospective study is to identify Non-Obstructive Myocardial Ischemia of patients who have acute chest pain using Magnetocardiography.
Interventions
DEVICEMagnetocardiography
Assessing the performance of magnetocardiography device for detecting non-obstructive myocardial ischemia using ultrasound coronary flow reserve (CFR) as the reference standard.
Sponsors
Qilu Hospital of Shandong University
Study design
Observational model
OTHER
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Age 18 years or older; * Patients with symptoms of myocardial ischemia such as angina pectoris, who have CAG showing \<70% stenosis at the most severe site or CTA showing non-severe stenosis * Signed informed consent.
Exclusion criteria
* Patients with absolute or relative contraindications to CFR-loaded myocardial perfusion, including acute myocardial infarction within 48 hours, significant left main coronary artery stenosis, bronchial asthma, and adenosine injection allergy; * Patients with Non-ischemic dilated cardiomyopathy, or hypertrophic cardiomyopathy, or moderate or severe valvular disease; * Patients with Hemodynamic instability (systolic blood pressure\<90 mmHg, or who requires vasoactive drugs), or patients with tachyarrhythmia, #degree atrioventricular block and above that have not returned to normal; * Patients who have severe renal abnormality with eGFR \<30 ml/min, or patients who are on dialysis; * Patients with malignant tumors with predicted survival of less than 1 year; * Pregnant or breastfeeding women; * Patients who are unable to enter the MCG device, who are unable to perform MCG examination due to interference from metal implants or other reasons, or who are deemed by the investigators to be unsuitable for enrollment.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Efficacy of MCG for the detection of Non-Obstructive Myocardial Ischemia | from the date of enrollment until the date of discharge, up to 30 days] | Establishing an algorithm model of MCG in identifying Non-Obstructive Myocardial Ischemia, the efficacy of the model was assessed by sensitivity, specificity |
Countries
China
Contacts
CONTACTJiaojiao Pang, Doctor
PRINCIPAL_INVESTIGATORYuguo Chen, Professor
Qliu Hospital of Shandong University
Outcome results
None listed