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Impact of Risk Feedback on Behavioral Trajectories

Alcohol Metabolism and Disease Risk in Asians: Examining the Impact of Personalized Phenotypic/Genotypic Feedback on Early Drinking Trajectories

Status
Not yet recruiting
Phases
Unknown
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT07657221
Enrollment
450
Registered
2026-06-18
Start date
2026-08-18
Completion date
2030-08-31
Last updated
2026-06-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Alcohol Consumption, Healthy

Brief summary

The goal of this study is to examine the effects of providing personalized information about behavioral, physical, and genetic factors that are associated with elevations in risk for some health problems. The main research question is: can we affect young adult behaviors through communication about these health-related risks? Participants will be asked to complete an in-person baseline session where they provide a DNA sample, complete online surveys, and do a brief interview. They will then receive one of several brief online information sessions and be followed in online surveys approximately every 3 months over the next 2 years.

Interventions

BEHAVIORALPHEN feedback

Feedback on alcohol response (phenotype)

GENETICPHEN+GENE Feedback

Feedback on both phenotype and genotype (PHEN+GENE)

OTHERControl

Feedback that serves as control

Sponsors

University of Southern California
Lead SponsorOTHER
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
CollaboratorNIH

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
SINGLE (Subject)

Eligibility

Sex/Gender
ALL
Age
17 Years to 25 Years
Healthy volunteers
Yes

Inclusion criteria

* USC student of Chinese, Japanese, Korean, or Vietnamese heritage

Exclusion criteria

* not a USC student, not 17-25 years old, not of Chinese, Japanese, Korean, or Vietnamese heritage

Design outcomes

Primary

MeasureTime frameDescription
Drinking frequencyup to 2 years post-interventionNumber of days consumed alcohol
Average alcohol quantityup to 2 years post-interventionAverage amount of alcohol consumed on drinking days

Secondary

MeasureTime frameDescription
Amount of alcohol consumedup to 2 years post-interventionTotal number of drinks consumed
Maximum daily alcoholup to 2 years post-interventionHighest number of drinks consumed on one day
Use of flush curesup to 2 years post-interventionProportion of drinking days used flush cures
Use of drinking behavioral strategiesup to 2 years post-interventionProportion of drinking days used behavioral strategies

Countries

United States

Contacts

CONTACTSusan Luczak, PhD
luczak@usc.edu2137402203
PRINCIPAL_INVESTIGATORSusan Luczak, PhD

University of Southern California

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Jun 19, 2026