HoLEP (Holmium Laser Enucleation of Prostate), Hyperchloremia, Perioperative Management
Conditions
Brief summary
This study aims to evaluate the changes between preoperative and postoperative serum chloride levels in patients undergoing HoLEP surgery and to investigate the metabolic and clinical effects of this change. The study is observational, and no additional interventions will be performed.
Detailed description
Although isotonic irrigation fluids used in HoLEP surgery reduce the risk of hyponatremia associated with TUR syndrome, high-volume fluid absorption may lead to hyperchloremia and subsequent metabolic acidosis. This prospective, observational, single-center study, conducted at Ankara Bilkent City Hospital, aims to identify early markers of this condition to optimize perioperative management.
Interventions
PROCEDUREHoLEP surgery
All parameters are part of routine clinical practice; no additional examinations are required
Sponsors
Ankara City Hospital Bilkent
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
MALE
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* Patients scheduled for elective HoLEP surgery. * Patients providing written informed consent
Exclusion criteria
* Preoperative metabolic acidosis. * Advanced renal failure. * Emergency surgery. * Missing data.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in serum chloride level | Perioperative |
Secondary
| Measure | Time frame |
|---|---|
| irrigation volume | Perioperative |
| Arter blood gas | Perioperative |
Outcome results
None listed