Duration of Analgesia, Pain Score
Conditions
Brief summary
The aim of this study is to evaluate the effects of adding 5-mcg dexmedetomidine to hyperbaric bupivacaine in our population as it has never been published before, to enhance the duration of analgesia after perianal procedures requiring spinal saddle block and, thus reducing requirements of postoperative analgesics.
Interventions
DRUGDexmedetomidine
dexmedetomidine 5 microgram added to 5 mg of 0.5% hyperbaric bupivacaine in dextrose injection
5 mg of 0.5% hyperbaric bupivacaine in dextrose injection alone
Sponsors
Liaquat National Hospital & Medical College
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
40 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
* Patients undergoing elective perianal surgery under spinal saddle block were included in the study. * Age between 40-80 years * ASA status I and II
Exclusion criteria
* Pregnant women * Patient with coagulopathy * Infection at or near the needle insertion site * Allergy to the trial drug * Patient with chronic pain * Cognitive impairment * Patient with known drug or substance abuse
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Duration of analgesia | 0 hour to 4 hours | duration of analgesia was assessed from induction of anesthesia till patient discharge |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Pain score | Two hours post surgery till 24 hours | Pain will be assessed using Numeric Rating Scale (NRS) scale ranging from 0-10; 0 being no pain and 10 indicates the worst pain |
Countries
Pakistan
Outcome results
None listed