Fanconi Anemia
Conditions
Brief summary
This study being done to learn more about the use of medical Magnetic Resonance Imaging (mMRI) and dedicated dental MRI (ddMRI) as a non-invasive diagnosing tool when evaluating potential oral cancerous and precancerous lesions in Fanconi Anemia patients.
Interventions
DIAGNOSTIC_TESTMRIs
mMRI and ddMRI
Sponsors
University of Minnesota
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patients with a diagnosis of Fanconi Anemia who are willing to participate and willing to have MRIs * Willing to provide informed consent
Exclusion criteria
* Patient without diagnosis of FA * Patients with FA who are under the age of 18 * Unable to tolerate any MRI due to claustrophobia * Any contraindication for the MRI * Unable to provide informed consent or comply with the study protocol
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| sensitivity of mMRI and ddMRI in identifying dysplastic and malignant lesions in FA patients. | Immediately after MRI | Proportion of positive lesions correctly diagnosed |
| specificity of mMRI and ddMRI in identifying dysplastic and malignant lesions in FA patients. | Immediately after MRI | Proportion of negative lesions correctly diagnosed |
Countries
United States
Contacts
CONTACTCarla Campbell, BS
PRINCIPAL_INVESTIGATORRachel Uppgaard
University of Minnesota
Outcome results
None listed