Breast Cancer - Female
Conditions
Brief summary
The goal of this clinical trial is to find the difference in immune response between two types of regional anesthesia in female patients suffering from breast cancer. The main question it aims to answer is there a difference in the immune response between paravertebral block and erector spinal plane block. Hypothresis of the study is that paravertebral block with propofol induces less immune response in surgical treatment of breast cancer patients than erector spinal plane block. Participants will be asked to sign the informant consent. They will be given either paravertebral block or erector spinae plane block with general anesthesia using propofol. Their venous blood will be taken 1 hour prior surgery and 24 and 48 hours after surgery.
Interventions
PROCEDURERegional Anesthetic Injection
Draw of venous blood and application of paravertebral and erector spinae plane block
Draw of venous blood 24 hours after surgery
Sponsors
Clinical Hospital Center Rijeka
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
FEMALE
Age
18 Years to 70 Years
Healthy volunteers
No
Inclusion criteria
* ASA I and ASA II status, normal BMI
Exclusion criteria
* ASA III and ASA IV status, coagulopathy, chronic opioid use, diabetes, local infection of the skin
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Immune response in two different regional anesthesia techniques | From enrollment to 30 days post surgery |
Contacts
CONTACTJan Maroević, medical doctor
Outcome results
None listed