Adolescent Eating Disorders, Eating Disorders, Nervosa Adolescent
Conditions
Brief summary
This study aims to evaluate the clinical, psychological, and functional outcomes of adolescents with anorexia nervosa receiving multidisciplinary care in hospital settings. Participants are treated either in a day hospitalization program or in a full-time inpatient program, in accordance with the French national guidelines (Haute Autorité de Santé, HAS) for the management of anorexia nervosa. The study seeks to better understand the evolution of patients' health status over time, including nutritional, psychological, and social dimensions, and to identify factors associated with treatment response. Data will be collected as part of routine clinical care without modification of the standard therapeutic management. The results of this study may help improve clinical practices and optimize care pathways for adolescents with anorexia nervosa.
Interventions
Participants admitted to the day hospital receive a multidisciplinary treatment program including psychiatric, medical, nutritional, and psychosocial care, delivered through structured daytime sessions without overnight stay.
OTHERStandard Care Outside Day Hospital Program
Participants not admitted to the day hospital program receive usual care according to standard clinical pathways outside the specialized day hospital setting.
Sponsors
Fondation Santé des Étudiants de France
Study design
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Intervention model description
Participants are assigned to groups based on admission status to a specialized day hospital program for eating disorders. This is a non-randomized quasi-experimental study comparing individuals admitted to the program and those not admitted, with outcomes assessed over time.
Eligibility
Sex/Gender
ALL
Age
12 Years to 22 Years
Healthy volunteers
No
Inclusion criteria
* Adolescents and young adults aged 12 to 22 years * Diagnosed with an eating disorder * Referred for admission to the day hospital program between October 2019 and December 2023 * Provided informed consent (and parental consent for minors)
Exclusion criteria
* Refusal to participate * Age below 12 years or above 22 years
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in Body Mass Index (BMI) | From admission request to at least 18 months follow-up |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Change in eating disorder psychopathology assessed by EDE-Q | Baseline (at admission), discharge (end of hospitalization), and follow-up at least 18 months after admission | Eating disorder psychopathology will be assessed using the Eating Disorder Examination Questionnaire (EDE-Q), a self-report scale ranging from 0 to 6, with higher scores indicating more severe symptoms. The assessment will be performed at admission and discharge. |
| Change in body image concerns assessed by BSQ | Baseline (at admission), discharge (end of hospitalization), and follow-up at least 18 months after admission | Body image concerns will be assessed using the Body Shape Questionnaire (BSQ), a self-report scale with higher scores indicating greater body dissatisfaction. The assessment will be performed at admission and discharge. |
| Change in anxiety and depression symptoms assessed by HADS | Baseline (at admission), discharge (end of hospitalization), and follow-up at least 18 months after admission | Anxiety and depression symptoms will be assessed using the Hospital Anxiety and Depression Scale (HADS), which includes subscales for anxiety and depression, each ranging from 0 to 21, with higher scores indicating greater symptom severity. The assessment will be performed at admission and discharge. |
| Change in obsessive-compulsive symptoms assessed by MOCI | Baseline (at admission), discharge (end of hospitalization), and follow-up at least 18 months after admission | Obsessive-compulsive symptoms will be assessed using the Maudsley Obsessive-Compulsive Inventory (MOCI), where higher scores indicate more severe symptoms. The assessment will be performed at admission and discharge. |
| Change in eating disorder-related quality of life assessed by EDQoL | Baseline (at admission), discharge (end of hospitalization), and follow-up at least 18 months after admission | Quality of life related to eating disorders will be assessed using the Eating Disorders Quality of Life (EDQoL) questionnaire, with higher scores indicating greater impairment. The assessment will be performed at admission and discharge |
| Change in autistic traits assessed by AQ-10 | Baseline (at admission), discharge (end of hospitalization), and follow-up at least 18 months after admission | Autistic traits will be assessed using the Autism Spectrum Quotient (AQ-10), a brief screening tool with higher scores indicating more pronounced autistic traits. The assessment will be performed at admission and discharge |
| Change in family functioning assessed by FAD-12 | Baseline (at admission), discharge (end of hospitalization), and follow-up at least 18 months after admission | Family functioning will be assessed using the Family Assessment Device (FAD-12), with higher scores indicating poorer family functioning. The assessment will be performed at admission and discharge. |
Outcome results
None listed