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Hemodialysis Catheter Complications in the Emergency Department Versus Hemodialysis Unit

Comparison of the Risk of Catheter Thrombosis and Catheter-Related Infection Between Patients Undergoing Hemodialysis Catheter Insertion in the Emergency Department and Those Undergoing Catheter Insertion in the Hemodialysis Unit: A Prospective Observational Study

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT07645365
Enrollment
398
Registered
2026-06-12
Start date
2024-12-01
Completion date
2025-12-11
Last updated
2026-06-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Kidney Failure, Catheter-Related Infections, Catheter Thrombosis, Hemodialysis Catheter Complication, Hemodialysis Vascular Access

Keywords

Catheter-related infection, Dialysis catheter complications, Emergency department, Hemodialysis catheter

Brief summary

This prospective observational cohort study was designed to compare the risk of catheter thrombosis and catheter-related infection between adult patients who underwent temporary hemodialysis catheter insertion in the emergency department and those who underwent catheter insertion in the hemodialysis unit. The study was conducted at Antalya Training and Research Hospital. Adult patients aged 18 years and older who underwent hemodialysis catheter insertion in either the emergency department or the nephrology hemodialysis unit were included. A total of 398 patients were enrolled between December 1, 2024, and December 1, 2025. Demographic and clinical data were collected, and catheter-related complications occurring within 10 days after catheter insertion were assessed using hospital records and follow-up data.

Detailed description

Hemodialysis catheters are frequently used as temporary vascular access in patients requiring urgent or ongoing hemodialysis. Although these catheters provide rapid access for dialysis, catheter-related complications such as thrombosis and infection may result in catheter dysfunction, interruption of dialysis, repeated catheter placement, increased morbidity, and additional healthcare burden. In emergency departments, temporary hemodialysis catheters are often inserted under urgent clinical conditions. Although standard aseptic and antiseptic measures are applied, factors such as limited preparation time, clinical instability of the patient, and the need for rapid dialysis may affect the risk of catheter-related complications. In contrast, catheter insertion in a hemodialysis unit is generally performed in a more controlled clinical environment. This prospective observational cohort study compared two groups of adult patients: those who underwent temporary hemodialysis catheter insertion in the emergency department and those who underwent catheter insertion in the nephrology hemodialysis unit. The primary focus was to evaluate whether the catheter insertion setting was associated with differences in the development of catheter thrombosis and catheter-related infection within ten days after catheter placement. The study included 398 adult patients treated at Antalya Training and Research Hospital between December 1, 2024, and December 1, 2025. Demographic and clinical data were collected, and complications occurring within ten days after catheter insertion were assessed using hospital records and follow-up data. The findings of this study may help determine whether additional preventive measures are needed for hemodialysis catheter insertion procedures performed in emergency department settings.

Interventions

None listed

Sponsors

Antalya Health Sciences University
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Patients aged 18 years or older * Patients who underwent temporary hemodialysis catheter insertion in the emergency department * Patients who underwent temporary hemodialysis catheter insertion in the hemodialysis unit * Patients who agreed to participate in the study

Exclusion criteria

* Patients younger than 18 years of age * Patients who did not agree to participate in the study * Patients with known platelet function disorder * Patients with hematologic diseases, including malignancy * Immunosuppressed patients

Design outcomes

Primary

MeasureTime frameDescription
Incidence of Catheter-Related InfectionWithin 10 days after hemodialysis catheter insertionThe incidence of catheter-related infection will be assessed in adult patients who underwent temporary hemodialysis catheter insertion in either the emergency department or the hemodialysis unit. Catheter-related infection will be recorded based on clinical evaluation, laboratory findings when available, and hospital records during the 10-day follow-up period after catheter insertion.
Incidence of Catheter ThrombosisWithin 10 days after hemodialysis catheter insertionThe incidence of catheter thrombosis will be assessed in adult patients who underwent temporary hemodialysis catheter insertion in either the emergency department or the hemodialysis unit. Catheter thrombosis will be recorded based on clinical evaluation and hospital records during the 10-day follow-up period after catheter insertion.

Countries

Turkey (Türkiye)

Contacts

PRINCIPAL_INVESTIGATORMEHMET AKCIMEN

University of Health Sciences, Antalya Training and Research Hospital

STUDY_CHAIRMURAT DUYAN

University of Health Sciences, Antalya Training and Research Hospital

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Jun 23, 2026