Electrolytic Surface Decontamination in the Surgical Treatment of Peri-implantitis: A Randomized Clinical Trial

Effectiveness of Electrolytic Surface Decontamination in the Surgical Treatment of Peri-Implantitis: A Randomized Controlled Clinical Trial

Status

Not yet recruiting

Phases

Unknown

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT07644975

Enrollment

Registered

2026-06-12

Start date

2026-08-01

Completion date

2029-08-01

Last updated

2026-06-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Peri-implantitis

Keywords

Peri-implantitis, Electrolytic Surface Decontamination, Implant Surface Decontamination

Brief summary

The goal of this clinical trial is to learn whether adjunctive electrolytic surface decontamination can improve the outcomes of surgical treatment of peri-implantitis. The main questions it aims to answer are: * Does electrolytic surface decontamination reduce probing pocket depth more effectively than conventional surgical treatment alone? * Does electrolytic surface decontamination improve bleeding on probing, suppuration, and radiographic bone levels? Researchers will compare conventional surgical treatment plus electrolytic surface decontamination with conventional surgical treatment alone. Participants will: * Receive surgical treatment for peri-implantitis * Be randomly assigned to one of the two treatment groups * Attend follow-up visits for clinical and radiographic examinations * Undergo assessment of probing pocket depth, bleeding on probing, suppuration, and bone level changes during follow-up

Interventions

PROCEDUREElectrolytic Surface Decontamination

Electrolytic implant surface decontamination performed using the GalvoSurge system as an adjunct to conventional surgical treatment. The procedure is intended to remove biofilm and contaminants from the implant surface through an electrolytic cleaning process.

PROCEDUREConventional Surgical Treatment

Conventional surgical treatment of peri-implantitis consisting of flap elevation, mechanical implant surface decontamination using a titanium brush, and hydrogen peroxide application according to the study protocol.

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

SINGLE (Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

Adults aged 18 years or older Diagnosis of peri-implantitis requiring surgical treatment Presence of at least one dental implant diagnosed with peri-implantitis Ability and willingness to attend follow-up visits Provision of written informed consent

Exclusion criteria

Pregnancy or lactation Uncontrolled systemic diseases that may affect healing Immunosuppressive therapy History of head and neck radiotherapy Current use of medications known to affect bone metabolism Inability to comply with the study protocol or follow-up schedule Previous surgical treatment of peri-implantitis at the study implant site

Design outcomes

Primary

Measure	Time frame	Description
Change in Probing Pocket Depth (PPD)	24 Months	Change in peri-implant probing pocket depth (PPD) measured in millimeters at treated implant sites. The difference between baseline and 24-month follow-up measurements will be evaluated.

Countries

Turkey (Türkiye)

Contacts

CONTACTVolkan Arısan, Professor

varisan@istanbul.edu.tr+90 2124400000

PRINCIPAL_INVESTIGATORVolkan Arısan, Professor

Istanbul University Faculty of Dentistry

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Jun 13, 2026