Temporomandibular Joint Disc Displacement, With Reduction
Conditions
Keywords
tmj, disc displacement with reduction, jaw tracking, hyaluronic acid, prp, Temporomandibular Disorders, Zebris, Joint clicking, Maximum Mouth Opening, Intra-articular Injection
Brief summary
Assessment of intra-articular injection of hyaluronic acid and prp within TMJ using the Zebris jaw tracking device as an objective method
Interventions
COMBINATION_PRODUCTHyaluronic Acid (HA) and Platelet rich plasma
A combination of Autologous Platelet-Rich Plasma prepared from the patient's blood and hyaluronic acid injected intra-articularly
Sponsors
Mansoura University
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE
Masking description
The clinical outcomes assessor and MRI assessor were blinded to the intervention details during outcome assessment.
Eligibility
Sex/Gender
ALL
Age
18 Years to 45 Years
Healthy volunteers
No
Inclusion criteria
1. The patients' ages range from 18 to 45. 2. Patients experienced clicking sounds, painful joints, and restricted mouth opening. 3. Individuals whose MRI confirms a unilateral internal abnormality with reduction. 4. A patient who did not respond to conservative treatment. 5 • The patient's capacity and willingness to finish the course of therapy and subsequent appointments.
Exclusion criteria
1. A patient suffering from a connective tissue or inflammatory condition. 2. A patient who has had TMJ surgery in the past. 3. A history of injecting any kind of material into the target TMJ. 4. Drug allergy history. 5. A patient who has previously had fibrous or bony adhesion. 6. A patient experiencing psychological issues.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Mandibular movements assessed using the zebris JMA | Baseline, 1month | changes in mandibular movements assessed using the Zebris Jaw Motion Analyzer (JMA) system following treatment |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Pain Assessment using the Visual Analogue Scale | baseline, 1 week, 1 month, 3months, 6 months | Changes in pain intensity assessed using the Visual Analog Scale (VAS), a 0-10 scale where 0 indicates no pain and 10 indicates the worst imaginable pain; higher scores indicate greater pain severity. Measurements will be obtained at baseline, 1 week, 1 month, 3 months, and 6 months following intra-articular injection of hyaluronic acid and platelet-rich plasma (PRP) in patients with temporomandibular joint disc displacement with reduction. |
| clicking sound | Baseline, 6 months | changes in clicking sound following treatment |
| MRI assessment of the temporomandibular joint | At baseline and 6 months after treatment | MRI assessment of the temporomandibular joint, including disc position and retrodiscal tissue changes, |
Countries
Egypt
Outcome results
None listed